淋巴结转移率在头颈鳞状细胞癌患者预后评估中的研究进展  

Prognostic Value of Lymph Node Metastasis Ratio in Patients with Head and Neck Squamous Cell Carcinoma

作　　者：于天娇 李慧军[1] 刘江涛[1] 王启威[1] YU Tianjiao;LI Huijun;LIU Jiangtao;WANG Qiwei(Department of Otolaryngology,the First Affiliated Hospital of Harbin Medical University,Harbin 150001,China)

机构地区：[1]哈尔滨医科大学附属第一医院耳鼻咽喉头颈外科

出　　处：《医学综述》2019年第16期3216-3220,共5页Medical Recapitulate

摘　　要：头颈部鳞状细胞癌(HNSCC)是常见的恶性程度较高的肿瘤,复发和转移率较高,且预后较差。出现颈部淋巴结转移的HNSCC患者通常需行颈部淋巴结清扫术以清除颈部转移灶。目前,临床最常用的肿瘤分期系统是TNM分期,其中N代表的区域淋巴结受累情况,是HNSCC患者重要的预后因素。然而,近年来淋巴结转移率(LNR)已广泛应用于乳腺癌、胃癌等疾病的分期中。随着相关研究的不断进展,LNR能较现有N分期更好地评估HNSCC患者的预后。Head and neck squamous cell carcinoma(HNSCC) is one of the most common carcinomas with high degree of malignancy,and high incidence of recurrence and metastasis with poor prognosis.HNSCC patients with cervical lymph node metastasis usually need cervical lymph node dissection to remove cervical metastases.According to the most popular TNM classification system,regional lymph node involvement represented by N is the most important prognostic factor. However ,in recent years,the lymph node metastasis ratio(LNR),which is the ratio of the number of lymph node metastases to the total number of lymph nodes examined,has been widely used in the staging of diseases such as breast cancer and gastric cancer.With the progress of the related studies,it′s believed that LNR could better evaluate the risk of recurrence and overall survival of patients than the conventional N staging.

关 键 词：头颈鳞状细胞癌 淋巴结转移率 颈部淋巴结清扫 

分 类 号：R739.6[医药卫生—肿瘤]