乳腺浸润性筛状癌的超声诊断与临床病理学对照分析  

Comparative analysis of ultrasound diagnosis and the clinicopathology results of invasive cribriform carcinoma of breast

作　　者：王海飞[1] 王冠杰[1] 曹云云[1] 龚晓萍 牛建梅[1] WANG Haifei;WANG Guanjie;CAO Yunyun;GONG Xiaoping;NIU Jianmei(Department of Ultrasound,International Peace Maternity and Child Health Hospital,School of Medicine,Shanghai Jiao Tong University, Shanghai 200030,China)

机构地区：[1]上海交通大学医学院附属国际和平妇幼保健院超声科

出　　处：《肿瘤影像学》2019年第4期232-236,共5页Oncoradiology

基　　金：上海市卫生和计划生育委员会科研课题(20184Y0317)

摘　　要：目的:探讨乳腺浸润性筛状癌(invasive cribriform carcinoma,ICC)的超声声像图表现及临床病理学特征,以提高对该疾病的认识及诊断水平。方法:收集2008年1月 2018年8月上海交通大学医学院附属国际和平妇幼保健院收治的21例经手术后病理学检查证实为乳腺ICC的患者,分析其超声声像图表现及临床病理学资料。结果:患者均为女性,发病年龄为33~78岁,中位年龄53岁,病灶均发生于单侧。42.9%(9/21)患者筛状结构达100%,23.8%(5/21)患者筛状结构为50%~99%,33.3%(7/21)患者筛状结构<50%;3例伴腋窝淋巴结转移。超声声像图表现:病灶内部均为低回声,5例内伴点状钙化,90%边界不清晰或欠清晰,95%形态不规则或欠规则,71.4%内部和(或)周边可测及血流信号。95.2%(20/21)患者超声诊断为乳腺影像报告和数据系统(breast imaging reporting and data system,BI-RADS)4A类及以上,1例诊断为BI-RADS 3类。结论:通过掌握乳腺ICC的超声表现及临床病理学特点,有望提高对该疾病的认识及诊断水平。Objective: To study the ultrasonographic appearances and clinical features of invasive cribriform carcinoma (ICC) of breast for improving the understanding and diagnosis results of the disease. Methods: Twenty-one cases of ICC confirmed by pathology examination after surgery in International Peace Maternity and Child Health Hospital from Jan. 2008 to Aug. 2018 were collected, and their ultrasonographic features and clinicopathological data were analyzed. Results: All patients were females. The age of onset was 33-78 years and the median age was 53 years old. All the lesions occurred unilaterally. 42.9%(9/21) cases had 100% sieve structure, 23.8%(5/21) cases had 50%-99% sieve structure and 33.3%(7/21) cases had less than 50% sieve structure. Three cases combined with axillary lymph node metastasis. Ultrasonographic features: all lesions manifest as hypoechoic nodules. Combined with punctate calcification in 5 cases. About 90% lesions showed unclear boundaries and about 95% lesions showed irregular shapes. Blood flow signals could be detected internally and (or) peripherally in 71.4% lesions. Ultrasound diagnosis results: 95.2%(20/21) cases were diagnosed as breast imaging reporting and data system (BI-RADS) 4A or above, and 1 case was diagnosed as BI-RADS 3. Conclusion: By reviewing the ultrasonographic features and clinicopathological features of ICC, we could improve the understanding and diagnosis results of this disease.

关 键 词：乳腺癌 浸润性筛状癌 超声 乳腺肿块 

分 类 号：R737.9[医药卫生—肿瘤] R445.1[医药卫生—临床医学]