MR引导下射频消融治疗乏血供原发性肝癌  

MR-guided radiofrequency ablation for treatment of hypovascular primary liver cancer

作　　者：吴伟达[1] 翁志成[1] 彭建扬[1] 张梅玉 张春生[1] WU Weida;WENG Zhicheng;PENG Jianyang;ZHANG Meiyu;ZHANG Chunsheng(Department of Interventional, the Affiliated Hospital of Putian University,Putian 351100, China)

机构地区：[1]莆田学院附属医院医疗集团介入科

出　　处：《中国介入影像与治疗学》2019年第9期540-544,共5页Chinese Journal of Interventional Imaging and Therapy

摘　　要：目的 探讨MR引导下射频消融(RFA)治疗乏血供原发性肝癌的有效性及安全性。方法 收集21例乏血供原发性肝癌患者,于3.0T MR引导下采用MR兼容多极射频针行RFA。术后即刻对病灶及并发症发生情况进行影像学评估;术后1个月行肝脏MR平扫+增强扫描,之后每2~3个月复查1次,随访至2018年6月,评估肿瘤复发率。结果 共消融29个病灶,术后即刻影像学评估均提示完全消融。15例术中及术后出现心率下降、疼痛、少量出血等并发症(15/21,71.43%)。共随访6~26个月,平均(10.23±4.26)个月,术后消融灶局部复发2例(2/21,9.52%)。结论 MR引导下RFA治疗乏血供原发性肝癌安全、有效,且复发率低,可在临床推广。Objective To investigate the efficacy and safety of MR-guided radiofrequency ablation (RFA) for treatment of hypovascular primary liver cancer. Methods Totally 21 patients with hypovascular primary liver cancer underwent RFA under guidance of 3.0T MR using MR compatible multipolar RF electrode. Immediate MRI evaluation of the ablated lesions and complications after RFA were performed. One month after operation, plain and dynamic enhanced MR scan of liver were performed, and then reexamination was done every 2-3 months until June 2018. The recurrence rate was observed. Results A total of 29 lesions were completely ablated among 21 patients assessing by immediate imaging. Complications such as low heart rate, pain and minor hemorrhage etc. occurred in 15 patients (15/21, 71.43%). The follow-up period was 6-26 months (mean [10.23±4.26] months). Local recurrence of ablated lesions was observed in 2 patients (2/21, 9.52%). Conclusion MR-guided RFA for treatment of hypovascular primary liver cancer is safe and effective with low recurrence rate, which could potentially be applied in clinical practices.

关 键 词：肝肿瘤 射频消融术 磁共振成像 介入治疗 

分 类 号：R735[医药卫生—肿瘤] R445[医药卫生—临床医学]