Specific and Selective Bacteriophages in the Fight against Multidrug-resistant Acinetobacter baumannii  

作　　者：Natalia Baginska Anna Pichlak Andrzej Gorski Ewa Jonczyk-Matysiak 

机构地区：[1]Bacteriophage Laboratory,Hirszfeld Institute of Immunology and Experimental Therapy,Polish Academy of Sciences,53-114 Wroclaw,Poland [2]Phage Therapy Unit,Hirszfeld Institute of Immunology and Experimental Therapy,Polish Academy of Sciences,53-114 Wroclaw,Poland [3]Department of Clinical Immunology,Transplantation Institute,Medical University of Warsaw,53-114 Warsaw,Poland

出　　处：《Virologica Sinica》2019年第4期347-357,共11页中国病毒学（英文版）

基　　金：supported by the statutory funds from the Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences

摘　　要：Acinetobacter baumannii causes serious infections especially in immunocompromised and/or hospitalized patients.Several A.baumannii strains are multidrug resistant and infect wounds,bones,and the respiratory tract.Current studies are focused on finding new effective agents against A.baumannii.Phage therapy is a promising means to fight this bacterium and many studies on procuring and applying new phages against A.baumannii are currently being conducted.As shown in animal models,phages against multidrug-resistant A.baumannii may control bacterial infections caused by this pathogen and may be a real hope to solve this dangerous health problem.Acinetobacter baumannii causes serious infections especially in immunocompromised and/or hospitalized patients. Several A. baumannii strains are multidrug resistant and infect wounds, bones, and the respiratory tract. Current studies are focused on finding new effective agents against A. baumannii. Phage therapy is a promising means to fight this bacterium and many studies on procuring and applying new phages against A. baumannii are currently being conducted. As shown in animal models, phages against multidrug-resistant A. baumannii may control bacterial infections caused by this pathogen and may be a real hope to solve this dangerous health problem.

关 键 词：ACINETOBACTER BAUMANNII BACTERIOPHAGES PHAGE therapy MULTIDRUG resistance(MDR) 

分 类 号：Q[生物学]