大脑中动脉区脑梗死患者侧支循环状况对预后的影响  

Effect of collateral circulation on prognosis in patients with cerebral infarction in middle cerebral artery region

作　　者：朱乃刚 ZHU Nai-gang(Department of Internal Medicine-Neurology,Shandong Feicheng People’s Hospital,Feicheng 271600,China)

机构地区：[1]山东省肥城市人民医院神经内科

出　　处：《中国现代药物应用》2019年第17期6-8,共3页Chinese Journal of Modern Drug Application

摘　　要：目的探讨大脑中动脉区脑梗死患者侧支循环状况对预后的影响.方法 86例大脑中动脉区脑梗死患者作为研究对象,按照经颅超声多普勒(TCD)结果分为侧支循环开放组和侧支循环未开放组,各43例.两组患者入院后均经常规治疗,两组患者均在入院时、入院14 d及入院6个月进行美国国立卫生研究院卒中量表(NIHSS)评分、Barthel指数(BI)评分以及改良Rankin量表(mRS)评分,并进行比较.结果侧支循环开放组患者入院时、入院14 d、入院6个月NIHSS评分分别为(6.62±0.17)、(4.03±0.25)、(3.61±0.21)分,均明显低于侧支循环未开放组的(7.92±0.23)、(5.77±0.31)、(4.72±0.25)分,差异具有统计学意义(P<0.05).侧支循环开放组患者入院时、入院14 d、入院6个月BI评分分别为(61.94±4.72)、(80.17±4.04)、(87.31±5.33)分,均明显高于侧支循环未开放组的(53.47±4.16)、(72.28±3.84)、(77.14±4.58)分,差异具有统计学意义(P<0.05).两组患者入院时mRS评分比较差异无统计学意义(P>0.05);侧支循环开放组患者入院14 d、入院6个月mRS评分分别为(2.14±0.47)、(1.89±0.21)分,均明显低于侧支循环未开放组的(3.12±0.29)、(3.01±0.33)分,差异具有统计学意义(P<0.05).结论大脑中动脉区脑梗死侧支循环开放患者预后明显优于侧支循环未开放患者.Objective To discuss the effect of collateral circulation on prognosis in patients with cerebral infarction in middle cerebral artery region. Methods A total of 86 patients with cerebral infarction in middle cerebral artery region as study subjects were divided into opened collateral circulation group and unopened collateral circulation group, with 43 cases in each group. Both groups received conventional therapy after admission. The National Institutes of Health stroke scale (NIHSS), Barthel index (BI) and modified Rankin scale (mRS) at admission, 14 d and 6 months after admission between the two groups were compared. Results Opened collateral circulation group had obviously lower NIHSS score at admission, 14 d and 6 months after admission respectively as (6.62±0.17),(4.03±0.25) and (3.61±0.21) points than (7.92±0.23),(5.77±0.31) and (4.72±0.25) points in unopened collateral circulation group. Their difference was statistically significant (P<0.05). Opened collateral circulation group had obviously higher BI score at admission, 14 d and 6 months after admission respectively as (61.94±4.72),(80.17±4.04) and (87.31±5.33) points than (53.47±4.16),(72.28±3.84) and (77.14±4.58) points in unopened collateral circulation group. Their difference was statistically significant (P<0.05). There was no statistically significant difference in mRS score between the two groups (P>0.05). Opened collateral circulation group had obviously lower mRS score at 14 d and 6 months after admission respectively as (2.14± 0.47) and (1.89±0.21) points than (3.12±0.29) and (3.01±0.33) points in unopened collateral circulation group. Their difference was statistically significant (P<0.05). Conclusion The prognosis of patients with opened collateral circulation in middle cerebral artery infarction is better than that of patients with unopened collateral circulation.

关 键 词：脑梗死 侧支循环 预后 

分 类 号：R743.3[医药卫生—神经病学与精神病学]