One-dimensional and two-dimensional nanomaterials for the detection of multiple biomolecules  

作　　者：Quan Wang Xudong Wang Min Xu Xiaoding Lou Fan Xia 

机构地区：[1]Engineering Research Center of Nano-Geomaterials of Ministry of Education, Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan 430074, China [2]Hubei Key Laboratory of Bioinorganic Chemistry & Materia Medica, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Wuhan 430074, China [3]Zhejiang Institute, China University of Geosciences Wuhan, Hangzhou 311305, China

出　　处：《Chinese Chemical Letters》2019年第9期1557-1564,共8页中国化学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China (Nos. 21525523, 21722507, 21574048, 21874121);the National Basic Research Program of China (973 Program, No. 2015CB932600);the National Key R&D Program of China (Nos. 2017YFA020800, 2016YFF0100800);Natural Science Foundation of Zhejiang Province of China (No. LY18B050002)

摘　　要：The complexity of biological samples determines that the detection of a single biomolecule is unable to satisfy actual needs. Moreover, the "false positives" results caused by a single biomolecule detections easily leads to erroneous clinical diagnosis and treatment. Thus, it is important for the homogenous quantification of multiple biomolecules in not only basic research but also practical application. As a consequent, a large number of literatures have been exploited to monitor multiple biomolecules in homogenous solution, enabling facilitating the development of the disease diagnosis, treatment as well as drug discovery. One-dimensional nanomaterials and two-dimensional nanomaterials have special physical and chemical properties, such as good electrochemical properties, stable structure, large specific surface area, and biocompatibility, which are widely used in electrochemical and fluorescent detection of biomolecules. This tutorial review highlights the recent development for the detection of multiple biomolecules by using nanomaterials including one-dimensional materials(1DMs) as well as twodimensional materials(2DMs).The complexity of biological samples determines that the detection of a single biomolecule is unable to satisfy actual needs. Moreover, the "false positives" results caused by a single biomolecule detections easily leads to erroneous clinical diagnosis and treatment. Thus, it is important for the homogenous quantification of multiple biomolecules in not only basic research but also practical application. As a consequent, a large number of literatures have been exploited to monitor multiple biomolecules in homogenous solution, enabling facilitating the development of the disease diagnosis, treatment as well as drug discovery. One-dimensional nanomaterials and two-dimensional nanomaterials have special physical and chemical properties, such as good electrochemical properties, stable structure, large specific surface area, and biocompatibility, which are widely used in electrochemical and fluorescent detection of biomolecules. This tutorial review highlights the recent development for the detection of multiple biomolecules by using nanomaterials including one-dimensional materials(1DMs) as well as twodimensional materials(2DMs).

关 键 词：ONE-DIMENSIONAL NANOMATERIALS TWO-DIMENSIONAL NANOMATERIALS DETECTION MULTIPLE TARGETS Biomolecules 

分 类 号：O6[理学—化学]