基于MRI分型的胚胎发育不良性神经上皮瘤的影像学分析及临床意义  

Imaging analysis and clinical significance of embryonic dysplastic neuroepithelioma based on MRI typing

作　　者：赵晶[1] 费小瑞 许实成 李丹[1] 邓克学 刘影[1] 吴海波 王昌新 韦炜 ZHAO Jing;FEI Xiao-rui;XU Shi-cheng(Department of Radiology,The First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei,230001,China)

机构地区：[1]中国科学技术大学附属第一医院(安徽省立医院)影像科,合肥230001 [2]中国科学技术大学附属第一医院(安徽省立医院)神经外科,合肥230001 [3]中国科学技术大学附属第一医院(安徽省立医院)病理科,合肥230001

出　　处：《放射学实践》2019年第9期969-974,共6页Radiologic Practice

摘　　要：目的:探讨基于MRI分型的胚胎发育不良性神经上皮瘤(DNET)的影像学特征。方法:回顾性分析经手术病理证实的11例大脑半球DNET的影像学资料,其中男4例,女7例,年龄4~47岁,平均年龄17.2岁。结果: 11例患者均以癫痫发病,病灶位于颞叶8例,额叶1例,顶叶2例,均为单发。依据MRI表现分为:Ⅰ型类囊性7例,Ⅱ型结节状2例,Ⅲ型发育异常样2例。按外科手术切除术式分为:病灶扩大切除4例,单纯病灶切除5例,病灶次全切除2例。术后病理均为DNET。术后随访6~41个月,均无病灶扩大或复发。依据癫痫Engel疗效分级标准分为:EngelⅠ级8例,EngelⅡ级3例。结论: DNET的MRI表现具有一定的特征性,通过MRI分型有助于外科手术方案的制定。Objective: To investigate the imaging features of embryonic dysplastic neuroepithelioma (DNET) based on MRI typing. Methods: The imaging data of 11 cases of DNET in cerebral hemisphere confirmed by operation and pathology were retrospectively analyzed,including 4 males and 7 females,aged from 4 to 47 years,with an average age of 17.2 years. Results: Eleven patients were diagnosed with epilepsy.There were 8 cases located in temporal lobe,1 case of frontal lobe and 2 cases of parietal lobe,all of which were single.According to MRI manifestations,there were 7 cases of type 1 cystic type,2 cases of type 2 nodular shape,and 2 cases of type 3 dysplasia.According to the types of surgical resection,there were 4 cases of enlarged resection,5 cases of simple resection,and 2 cases of subtotal resection.Postoperative pathology was DNET.All patients were followed up for 6 to 41 months without enlargement or recurrence.According to the Egel classification criteria of epilepsy,8 cases were identified as Engel Ⅰ and 3 cases as Engel Ⅱ. Conclusion: The MRI manifestations of DNET have certain characteristics,and the MRI typing is helpful to the establishment of surgical strategies.

关 键 词：胚胎发育不良性神经上皮瘤 脑肿瘤 磁共振成像 癫痫 外科手术 

分 类 号：R739.4[医药卫生—肿瘤] R445.2[医药卫生—临床医学]