Chiral Frustrated Lewis Pairs Catalyzed Highly Enantioselective Hydrosilylations of Ketones  

作　　者：Xiaoqin Liu Qiaotian Wang Caifang Han Xiangqing Feng Haifeng Du 

机构地区：[1]Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China [2]School of Chemical Science, University of Chinese Academy of Sciences, Beijing 100049, China

出　　处：《Chinese Journal of Chemistry》2019年第7期663-666,共4页中国化学（英文版）

基　　金：We are grateful for generous financial support from the National Natural Science Foundation of China (.21572231,21521002,and 21825108).

摘　　要：A highly enantioselective Piers-type hydrosilylation of simple ketones was successfully realized using a chiral frustrated Lewis pair of tri-tert-butylphosphine and chiral diene-derived borane as catalyst.A wide range of optically active secondary alcohols were furnished in 80%-99% yields with 81%-97% ee's under mild reaction conditions.

关 键 词：ENANTIOSELECTIVE Hydrosilylations of KETONES 

分 类 号：O6[理学—化学]