针刺结合康复疗法治疗脊髓损伤后肌肉痉挛的Meta分析  

Acupuncture Combined with Rehabilitation Therapy for Muscle Spasm after Spinal Cord Injury: A Meta-Analysis

作　　者：鄢来军 颜浪辉 唐焕章 Yan Laijun;Yan Langhui;Tang Huanzhang(Fujian University of Traditional Chinese Medicine,Fuzhou,350122,China;Key Laboratory of Education of the People’s Republic of China,Fuzhou,350122,China;900th Hospital of the Joint Logistics Support Force of PLA,Fuzhou,350122,China)

机构地区：[1]福建中医药大学中医学院,福建福州350122 [2]福建中医药大学中医骨伤及运动康复教育部重点实验室,福建福州350122 [3]解放军联勤保障部队第900医院,福建福州350122

出　　处：《成都中医药大学学报》2019年第3期67-72,共6页Journal of Chengdu University of Traditional Chinese Medicine

基　　金：南京军区联勤部卫生部重点项目(14ZX26)

摘　　要：目的:系统评价针刺结合康复疗法对于脊髓损伤后肌肉痉挛患者肢体功能的影响。方法:计算机检索PubMed、Cochrane Library、中国知网、维普、万方等数据库,检索时间为自其建库~2018年10月。获得与针刺结合康复疗法治疗脊髓损伤后肌肉痉挛的临床随机对照试验文献。采用RevMan5.3软件对相关结局指标进行Meta分析。结果:最终纳入文献11篇,均为中文文献,共纳入715例受试者。统计结果显示,实验组临床有效率高于对照组[MD=5.02,95%CI(3.05,8.28),Z=6.34,P<0.001];实验组患者临床痉挛指数评分指数的改善优于对照组[MD=-3.09,95%CI(-4.51,-1.67),Z=4.28,P<0.001];实验组患者Ashworth评分的改善优于对照组[MD=-0.84,95%CI(-1.01,-0.67),Z=9.48,P<0.001];实验组患者Barthel指数的改善优于对照组[MD=10.41,95%CI(8.74,12.09),Z=12.19,P<0.001];实验组与对照组均无不良事件发生报告。结论:研究显示针刺联合康复疗法相比于其他疗法,对于脊髓损伤患者肌肉痉挛效果更好。但由于纳入文献的局限性,需要更多的多中心、大样本的临床随机对照实验进一步证明。Objective:To systematically evaluate the effects of acupuncture combined with rehabilitation therapy on patients who are suffer from muscle spasm after spinal cord injury.Methods:PubMed,CochraneLibrary,China National Knowledge Infrastructure(CNKI) database,Wanfang data database and Chinese Science and Technology Periodical(VIP)database were retrieved from their inception to October,2018 by computer to obtain relative randomized controlled trials about acupuncture combined with rehabilitation therapy for muscle spasm after spinal cord injury.RevMan 5.3 software was used to analysis those datas and effect model which were useful.Results:A total of 11 articles,all of which were published in china,were included in this research.715 patients were included.The results showed that the efficient of the experimental group was better than that of the control group[MD=5.02,95%CI(3.05,8.28),Z=6.34,P <0.001];the clinical sputum index score of the experimental group was better than that of the control group[MD=-3.09,95%CI(-4.51,-1.67),Z=92.86,P <0.001];the Ashworth score of the experimental group was better than that of the control group[MD=-0.84,95%CI(-1.01,-0.67),Z=9.48,P <0.001];the Barthel index of the experimental group was better than that of the control group[MD=10.41,95%CI(8.74,12.09),Z=12.19,P <0.001];No negative or harmful results were reported.Conclusion:The present study have shown that acupuncture combined with rehabilitation therapy has a better effect on muscle spasm in patients with spinal cord injury than other therapies.Meanwhile,more multicenter and large-sample clinical randomized controlled trials are requested to overcome the limitations of the inclusion of the research.

关 键 词：脊髓损伤 痉挛 针刺 康复 META分析 

分 类 号：R744[医药卫生—神经病学与精神病学] R245.37[医药卫生—临床医学]