11例肺纤毛黏液结节性乳头状肿瘤临床分析  

Surgical treatment of ciliated muconodular papillary tumor of the lung:a report of 11 cases

作　　者：万紫微 黄威[1] 姜格宁[1] 侯立坤[2] Wan Ziwei;Huang Wei;Jiang Gening;Hou Likun(Department of Thoracic Surgery,Shanghai Pulmonary Hospital,Tongji University,School of Medicine,Shanghai 200433,China;Department of Pathology,Shanghai Pulmonary Hospital,Tongji University,School of Medicine,Shanghai 200433,China)

机构地区：[1]同济大学附属上海市肺科医院胸外科,200433 [2]同济大学附属上海市肺科医院病理科,200433

出　　处：《中华胸心血管外科杂志》2019年第9期520-522,共3页Chinese Journal of Thoracic and Cardiovascular Surgery

摘　　要：目的分析肺纤毛黏液结节性乳头状肿瘤的临床特点,旨在提高对此疾病的认识.方法收集2017年4月至2018年4月在本科室进行手术治疗的11例患者的临床资料,最终病理证实为肺纤毛黏液结节性乳头状肿瘤.其中男8例,女3例,平均年龄(63.7±5.6)岁.所有患者术前均行胸部CT检查,均接受胸腔镜肺切除术.结果影像学特点提示病灶主要位于肺外周,右下肺叶常见;病灶形态主要表现为磨玻璃病灶,可伴有空洞型病变,部分为实性结节.手术以胸腔镜肺局限性切除术为主,无中转开胸,无严重围手术期并发症.全组手术时间(78.0±28.2)min,术中失血量(37.3±14.9)ml,术后住院时间(3.45±0.93)天.3例术中冰冻提示肺原位癌或微浸润腺癌,但术后病理均为肺纤毛黏液结节性乳头状肿瘤.随访6~18个月,所有患者均生存,无复发病例.结论肺纤毛黏液结节性乳头状肿瘤发病罕见,无特异性临床表现,易误诊为肺原位癌或微浸润腺癌.胸腔镜肺切除术安全有效,预后良好.Objective To investigate the clinical features of ciliated muconodular papillary tumor(CMPT) of the lung. Methods We retrospectively reviewed 11 cases with final pathology being diagnosed as CMPT in our department from April 2017 to April 2018. There were 8 males and 3 females with a mean age of(63.7±5.6) years. The clinical data, histopathological features, treatment, and prognosis were reviewed. All patients received CT scan before operation. Results The radiological features of CMPT include: located peripherally and most in right lower lobe;most CMPT lesions are GGO, some with air spaces in center and few being solid. All patients underwent video-assisted thoracic surgery(VATS) successfully, and there were no severe perioperative complications. The mean operating time was(78.0±28.2) min. The mean blood loss was(37.3±14.9) ml. The mean postoperative hospital stays were(3.45±0.93) days. Pathology examination of all patients were CMPT. Follow-up time ranged from 6 to 18 months and no recurrence was found. Conclusion CMPT is rare tumor, without specific clinical manifestation, but sometimes misdiagnosed as adenocarcinoma in situ or minimally invasive adenocarcinoma. VATS is feasible and safe for CMPT, and the prognosis is good.

关 键 词：肺肿瘤 纤毛黏液结节性乳头状肿瘤 胸腔镜手术 预后 

分 类 号：R734.2[医药卫生—肿瘤]