真菌性食管炎650例临床分析  

Analysis of clinical characteristics of 650 cases of fungal esophagitis

作　　者：虎金朋 牛敏 杨珍 郑路路 王佩 周燕 莫丽蓉 张雪 白飞虎 Hu Jinpeng;Niu Min;Yang Zhen;Zheng Lulu;Wang Pei;Zhou Yan;Mo Lirong;Zhang Xue;Bai Feihu(Ningxia Medical University,Yinchuan 750004,China;First Clinical Medical College of Northwestern University for Nationalities,Yinchuan 750002,China;Department of Gastroenterology,People′s Hospital of Ningxia Hui Autonomous Region,Yinchuan 750002,China;Department of Intensive Care Unit,Guyuan People′ s Hospital of Ningxia Hui Autonomous Region,Guyuan 756000,China)

机构地区：[1]宁夏医科大学,银川750004 [2]西北民族大学第一临床医学院,银川750002 [3]宁夏人民医院消化内科,银川750002 [4]宁夏固原市人民医院ICU科,宁夏固原756000

出　　处：《中华消化病与影像杂志（电子版）》2019年第4期152-155,共4页Chinese Journal of Digestion and Medical Imageology(Electronic Edition)

基　　金：国家自然科学基金(81760440);中央引导地方科技发展专项(YDZX20176400004650);宁夏消化疾病临床医学研究中心(2018CXPT0075)

摘　　要：目的探讨真菌性食管炎的临床特点及内镜表现。方法收集2015年1月至2018年12月于宁夏回族自治区人民医院内镜中心行胃镜检查后诊断的650例真菌性食管炎患者的临床资料、内镜表现进行回顾性分析。结果共纳入650例真菌性食管炎患者,其检出人数呈逐年升高趋势,总检出率1.3%,但每年的检出率比较差异无统计学意义,主要好发于男性,以40~60岁的患者多见,以上腹痛、胸骨后不适为主要临床表现,好发于全段食管,镜下Kodsi分级以Ⅰ、Ⅱ级为主,主要合并疾病为慢性胃炎,其中95例患者中幽门螺杆菌阳性39例。结论真菌性食管炎的检出人数呈逐年增长趋势,且具有一定的临床特征,可为临床医师提供临床诊断决策。Objective To investigate the clinical features and endoscopic findings of fungal esophagitis.Methods The clinical data and endoscopic findings of 650 patients with fungal esophagitis diagnosed by endoscopy in Endoscopy Center of People′s Hospital of Ningxia Hui Autonomous Region from January 2015 to December 2018 were retrospectively analyzed.Results A total of 650 patients with fungal esophagitis were included,and the number of patients detected increased year by year.The total detection rate was 1.3%.However,the annual detection rate was not statistically significant,mainly in men,and more common in patients aged 40-60 years.The upper abdominal pain and post-sternal discomfort were the main clinical symptoms,which occurred in the whole esophagus.The microscopic Kodsi classification was mainly grade Ⅰ and Ⅱ.The main combined disease was chronic gastritis.Among them,39 cases were positive for Helicobacter pylori in 95 patients.Conclusion The number of detected fungal esophagitis is increasing year by year,and it has certain clinical features that can provide clinical diagnostic decisions for clinicians.

关 键 词：真菌性食管炎 胃镜 回顾性分析 

分 类 号：R571[医药卫生—消化系统]