成釉细胞瘤侵袭深度的初步测量研究  

Preliminary study of local invasion in ameloblastoma

作　　者：陆长玺 郭传瑸[2] LU Changxi;GUO Chuanbin(Department of General Dentistry, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine,National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai 200011)

机构地区：[1]上海交通大学医学院附属第九人民医院口腔医学院口腔综合科·国家口腔疾病临床医学研究中心,上海市口腔医学重点实验室,上海市口腔医学研究所,200011 [2]北京大学口腔医学院口腔颌面外科

出　　处：《现代口腔医学杂志》2019年第5期270-273,共4页Journal of Modern Stomatology

摘　　要：目的测量成釉细胞瘤的侵袭深度,比较各病理类型在侵袭深度上的差异,探讨不同临床因素对侵袭深度的影响。方法北京大学口腔医院颌面外科2005~2009年间收治的26例成釉细胞瘤患者,病例资料完整,有完整的大体标本。大体标本经过重新处理及石蜡包埋切片,最终符合测量条件的共20例。使用Olympus图像采集系统获取HE切片图像,运用计算机软件测量成釉细胞瘤侵袭深度,并用t检验及方差分析讨论侵袭性的影响因素。结果一般型及单囊型成釉细胞瘤的平均侵袭深度分别为1.674mm及1.545mm,两型间有差异,但不显著。一例特殊类型,角化型成釉细胞瘤侵袭深度为12.65mm。不同术式间侵袭深度差异显著,其他因素和侵袭深度无明显关系。结论单囊及一般型成釉细胞瘤侵袭深度较小,目前采用的5mm截骨边界已很充足,甚至可以适当减小;而多次复发的角化型成釉细胞瘤治疗则不应保守。各临床因素对侵袭性影响较小。Objective To measure the invasive depth of ameloblastoma , investigate the differences within pathologic types and ananlyze relative clinic factors. Methods 20 patients diagnosed as ameloblastoma were treated in Peking University School of Stomatology . Their specimens were reprocessed and embedded with paraffin for HE stain. Computer softwares were used to measure the invasion and the data were analyzed with t-test and ANOVA. Results The average invasive depth of classic and unicystic types were 1.674mm and 1.545mm, there were differences between the two types, but not significant The invasive depth of a keratoameloblastam was 12.65mm. The differences between surgical methods were significant, but other factors were not related to invasion depth. Conclusion The invasion of unicystic and classic type of ameloblastoma was not deep, the currently used 5mm safety margin was adequate, which even could be less. The treatment of keratoameloblastoma should not be conservative.

关 键 词：成釉细胞瘤 侵袭深度 病理类型 

分 类 号：R739.8[医药卫生—肿瘤]