胃癌腹膜转移患者行胃癌切除术及术后化疗的生存分析  

Survival analysis of gastric cancer patients with peritoneal metastasis after gastrectomy and postoperative chemotherapy

作　　者：周文考 赵国华[1] 吕武 王越[1] 林杰[1] Zhou Wenkao;Zhao Guohua;Lv Wu;Wang Yue;Lin Jie(Department of General Surgery,Cancer Hospital of China Medical University,Liaoning Cancer Hospital & Institute,Liaoning Shenyang 110042,China.)

机构地区：[1]辽宁省肿瘤医院(中国医科大学肿瘤医院)普通外科

出　　处：《现代肿瘤医学》2019年第21期3858-3861,共4页Journal of Modern Oncology

摘　　要：目的:探讨胃癌腹膜转移患者行手术及术后化疗的意义。方法:回顾性分析胃癌腹膜转移病例89例,收集有效随访病例的相关术前临床和病理学资料、术中探查所见转移方式、手术方式、术后处理措施等数据。结果:通过对患者临床病理学特征进行单因素分析显示,手术方式(P=0.004)、化疗(P=0.003)、腹膜转移方式(P<0.05)、Borrmann分型(P<0.05)对胃癌腹膜转移的预后生存具有显著性影响。结论:对于胃癌腹膜转移患者,无论患者转移程度如何,如果没有绝对手术禁忌证,建议行胃癌切除D1淋巴结清扫,术后配合化疗。Objective:To investigate the significance of operation and postoperative chemotherapy for patients with peritoneal metastasis of gastric cancer.Methods:89 cases of peritoneal metastasis of gastric cancer were retrospectively analyzed.The preoperative clinical and pathological data,the mode of metastasis,the choice of operative methods,and the treatment measures were collected.Results:Univariate analysis of the clinicopathological features of the patients showed that the prognosis and survival of gastric cancer with peritoneal metastasis were significantly affected by operation(P=0.004),chemotherapy(P=0.003),peritoneal metastasis(P<0.05)and Borrmann classification(P<0.05).Conclusion:For gastric cancer patients with peritoneal metastasis,regardless of the degree of metastasis,if there is no absolute surgical contraindication,gastrectomy D1 lymph node dissection is recommended,postoperative chemotherapy.

关 键 词：胃癌切除术 术后化疗 胃癌腹膜转移 生存 回顾性研究 

分 类 号：R735.2[医药卫生—肿瘤]