无症状健康体检人群结直肠息肉及腺瘤检出情况及与相关临床因素分析  

Detection of colorectal polyps and adenomas in asymptomatic health examination population and analysis of relevant clinical factors

作　　者：刘玲玲[1] 王国军[2] 许冬[1] 王婷婷[1] 付丽[1] 李丽[1] Liu Lingling;Wang Guojun;Xu Dong;Wang Tingting;Fu Li;Li Li(International Medical Center,Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China;Department of Surgery,Medical and Health Center,Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China)

机构地区：[1]首都医科大学附属北京友谊医院国际医疗中心,100050 [2]首都医科大学附属北京友谊医院医保中心外科,100050

出　　处：《国际外科学杂志》2019年第10期686-691,共6页International Journal of Surgery

摘　　要：目的了解无症状健康体检人群结直肠息肉及腺瘤检出情况及与各临床因素的关系。方法收集2018年1月—2019年3月在首都医科大学附属北京友谊医院国际医疗中心完成结肠镜检查的615例无症状健康体检者的结肠镜结果及临床资料,其中男性436例,女性179例;平均年龄47.38岁,年龄范围18~81岁;回顾性分析其性别、年龄、吸烟史、饮酒史及体重指数对结直肠息肉及腺瘤检出率的影响。采用χ^2检验及趋势χ^2检验比较不同人群结直肠息肉及腺瘤检出率差异,采用多因素Logistic回归分析与结直肠息肉及腺瘤检出率相关的因素。结果共检出结直肠病变者240例(检出率为39.02%),其中结直肠息肉206例(33.50%),结直肠腺瘤138例(22.44%)。在结直肠息肉检出率方面,男性高于女性[36.70%(160/436)比25.70%(46/179),χ^2=6.89,P<0.05],吸烟者高于不吸烟者[42.35%(108/255)比27.22%(98/360),χ^2=15.34,P<0.001],饮酒者高于不饮酒者[40.67%(109/268)比27.95%(97/347),χ^2=10.98,P<0.05],随着年龄增长,结直肠息肉检出率明显增高(χ^2=24.19,P<0.001),随着体重指数增高,结直肠息肉检出率明显增高(χ^2=16.88,P<0.001)。在结直肠腺瘤检出率方面,吸烟者高于不吸烟者[28.24%(72/255)比18.33%(66/360),χ^2=7.31,P<0.05],饮酒者高于不饮酒者[27.61%(74/268)比18.44%(64/347),χ^2=7.30,P<0.05],随着年龄增长,结直肠腺瘤检出率明显增高(χ^2=15.87,P<0.001),随着体重指数增高,结直肠腺瘤检出率明显增高(χ^2=13.30,P<0.001),而结直肠腺瘤检出率在男女方面无明显差异[24.31%(106/436)比17.88%(32/179),χ^2=3.02,P>0.05]。多因素Logistic回归分析结果显示,年龄增长、体重指数增高、吸烟、饮酒是结直肠息肉及腺瘤的危险因素。结论结直肠息肉及腺瘤检出率与性别、年龄、吸烟、饮酒及体重指数有一定关系,年龄增长、体重指数增高及吸烟是结直肠息肉的危险因素,年龄增长、体重指数增高是结直�Objective To analysis the incidence and relevant clinical factors of colorectal polyps and adenomas in population of health examination. Methods Colonoscopy results and clinical data of 615 cases undergoing health examination from January 2018 to March 2019 were analyzed retrospectively in International Medical Center, Beijing Friendship Hospital, Capital Medical University.There were 436 males and 179 females, average age 47.38 years, aged 18-81 years. The clinical data contained sex, age, smoking history, drinking history, body mass index.Chi-square test and trend chi-square test were used to compare the differences of polyp detection rate and adenoma detection rate in different populations. Multivariate Logistic regression analysis were applied to explore the potential factors associated with the polyp detection rate and adenoma detection rate. Results Two hundred and forty cases(39.02%) with colorectal disease were checked out, include 206 cases(33.50%) with colorectal polyps and 138 cases(22.44%) with colorectal adenomas. In the detection rate of colorectal polyps, male were higher than female[36.70%(160/436) vs 25.70%(46/179),χ^2=6.89, P<0.05], smokers were higher than non-smokers[42.35%(108/255) vs 27.22%(98/360),χ^2=15.34, P<0.001], and drinkers were higher than non-drinkers[40.67%(109/268) vs 27.95%(97/347),χ^2=10.98, P<0.05]. With the increase of age, the detection rate of colorectal polyps increased significantly(χ^2=24.19, P<0.001). With the increase of body mass index, the detection rate of colorectal polyps increased significantly(χ^2=16.88, P<0.001). In the detection rate of colorectal adenoma, smokers were higher than non-smokers[28.24%(72/255) vs 18.33%(66/360),χ^2=7.31, P<0.05], and drinkers were higher than non-drinkers[27.61(74/268)% vs 18.44%(64/347),χ^2=7.30, P<0.05]. With the increase of age, the detection rate of colorectal adenoma increased significantly(χ^2=15.87, P<0.001). With the increase of body mass index, the detection rate of colorectal adenoma increased significantly (χ^

关 键 词：结肠镜 腺瘤 无症状体检 结直肠息肉 

分 类 号：R735.34[医药卫生—肿瘤]