放射性口腔干燥症的评估与临床管理的研究进展  

Research progress on the evaluation and management of radiation-induced xerostomia

作　　者：陈东 杨征[1] 蒋丽[1] Chen Dong;Yang Zheng;Jiang Li(State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept.ofGeneral Dentistry,West China Hospital of Stomatology,Sichuan University,Chengdu 610041,China)

机构地区：[1]口腔疾病研究国家重点实验室国家口腔疾病临床医学研究中心四川大学华西口腔医院全科门诊

出　　处：《国际口腔医学杂志》2019年第6期711-717,共7页International Journal of Stomatology

摘　　要：放射性口腔干燥症是头颈部肿瘤放射治疗术后常见的并发症,严重影响了患者的生存质量。本文主要讨论放射性口腔干燥症的评估方法,包括唾液分泌功能检测、影像学检查方法和主观评估方法,以及放射治疗前、中、后期对口腔干燥症的临床管理措施,为降低放射性口腔干燥症的发生率、缓解症状及提高患者的生存质量提供了理论依据和方法。Radiation-induced xerostomia is a common complication after radiotherapy for head and neck cancer. It significantly affects quality of life in survivors of head and neck cancer. In this review, the evaluations of xerostomia including saliva secretion function, imaging examinations and subjective measurements were discussed, as well as the management before, during and after radiotherapy. They provided evidence and approach for reducing morbidity of xerostomia and increasing quality of life in patients under radiotherapy.

关 键 词：头颈部肿瘤 放射治疗 口腔干燥症 唾液腺 生存质量 

分 类 号：R730.55[医药卫生—肿瘤]