分子对接技术在天然产物小分子与靶标蛋白相互作用中的研究进展  

The Use of Synchrotron Vacuum Ultraviolet Photoionization in the Study of Secondary Organic Aerosol

作　　者：曹茂启 王珏[1] 罗骏[1] 刘德见 Cao Maoqi;Wang Jue;Luo Jun;Liu Dejian(Qiannan Normal University for Nationalities, Duyun 558000;National The People’s Hospital of Qiannan, Duyun 558000, China)

机构地区：[1]黔南民族师范学院,贵州都匀558000 [2]黔南州人民医院,贵州都匀558000

出　　处：《广东化工》2019年第19期109-109,130,共2页Guangdong Chemical Industry

基　　金：黔科合LH字[2015]7705;黔教合KY字[2016]110,qnsyrc201505

摘　　要：天然产物小分子配体与靶标蛋白的相互作用是很多生物学过程的核心,精确预测其相互作用的模式在现代药物设计中具有重要的基础意义。本文系统的介绍了分子对接技术在天然产物小分子与靶标蛋白相互作用中的研究进展。The interaction between natural small molecular ligands and target proteins is the core of many biological processes. Accurate prediction of their interaction patterns is of fundamental significance in modern drug design. In this paper, the progress of molecular docking technology in the interaction between small molecules of natural products and target proteins is reviewed systematically.

关 键 词：天然产物小分子 靶标蛋白 分子对接 

分 类 号：TQ[化学工程]