胃癌肥大细胞与微血管密度的关系  

Relationship Between Mast Cell Density and Microvessel Density in Gastric Carcinoma

作　　者：张友元[1] 江应安[1] 魏爱君[1] 肖和平[1] 熊密[2] 

机构地区：[1]黄石市中心医院,黄石435000 [2]华中科技大学同济医学院,武汉430030

出　　处：《武汉大学学报（医学版）》2002年第4期357-358,共2页Medical Journal of Wuhan University

基　　金：湖北省科枝厅重点发展计划项目(批准号:20002B21)

摘　　要：目的:探讨胃癌组织肥大细胞密度（MCD）与微血管密度（MVD）的关系。方法:俾士麦棕法显示胃癌MC,单克隆抗体CD34标记血管内皮。结果:MCD与MVD存在直线回归关系:Y=3.92+0.943X,r=0.512。MCD低计组（≤21）病例MVD与MCD高计组（>21）病例MVD比较,差异有显著性（P<0.01）。结论:胃癌组织MC可能有刺激血管增生的作用。Objective: To evaluate the relationship between mast cell density (MCD) and microvessel density (MVD) in gastric carcinoma. Methods: Bismark brown staining method was used for the observation of MC, and monoclonal antibody CD43 was used for marking the endothelial surface. Results: The relation of linear regression between MCD and MVD was revealed: Y = 3 .92 + 0.943X, r = 0.512. MVD had significant difference compared with MCD low group and high group ( P < 0.01) . Conclusion: MC could stimulate growth of neoangiogenesis in gastric carcinoma.

关 键 词：胃癌 肥大细胞 微血管密度 病理 

分 类 号：R735.202[医药卫生—肿瘤]