110keVFe^+离子束对氨基酸衍生物的辐射分解  

Radiolysis of Amino Acid Derivatives Induced by the Irradiation of 110ke V Fe^+ Ion Beams

作　　者：袁世斌[1] 卫增泉 高清祥[2] 李海燕[2] 

机构地区：[1]中国科学院近代物理研究所,兰州730000 [2]兰州大学生命科学学院,兰州730000

出　　处：《物理化学学报》2002年第11期1033-1037,共5页Acta Physico-Chimica Sinica

基　　金：国家自然科学基金(19975060);中国科学院"九五"基础性研究重点项目(KJ952-S1-424)

摘　　要：用200kV离子注入机提供的110keVFe+离子束注入L(+)-半胱氨酸盐酸盐单晶水合物薄膜样品,离子注量为2.5×1016ions·cm-2.离子注入后刮下薄膜进行简单固态混和,在傅里叶变换红外光谱仪、高效液相色谱仪和电喷雾电离-傅里叶变换质谱仪上对离子注入前后的样品分别进行了测试.对离子注入样品的两次红外光谱分析结果有所不同,表明薄膜样品不同部位受低能铁离子束辐照后可发生不同的辐射分解,但二者又具有一定的相似性,都反映了原分子中氨基、羧基和巯基等基团的受损和新的硝基的生成.高效液相色谱和傅里叶变换质谱分析表明,离子注入样品中产生了多种不同分子量的新分子,证实110keVFe+离子束能够引起氨基酸衍生物的辐射分解.keV Fe + ion beams supplied by 200kV ion injec tor wer e implanted into film samples of L(+)-cysteine hydrochloride monohydra te.T he dose was 2.5×10 16 ions·cm-2 .After the implantation,the film sa m-ples were scraped down and simply m ix ed together in the solid state.The sa mples before and after ion implantatio n were tested on FTIR,HPLC and ESI-FTM S spectroscope respectively.The tw o r esults of FTIR spectroscopic tests of the ion-implanted samples were di fferent ,which showed that radiolysis might have taken place at differen t sites of the film.But there is certain simi larity between the two results in that they bot h showed the damages of the amino,carboxyl and sulfhydryl grou ps,and so on,o f the original molecul es and the formation of new nitro groups.The formation o f many new mol ecules with various molecular weights was determined by HPLC and FTMS analysis and radiolysis of amin o acid derivatives induced by the irr adiat ion of 110keV Fe + ion beams was confirmed.

关 键 词：衍生物 重离子束 氨基酸 辐射分解 红外光谱 高效液相色谱 质谱 铁离子 

分 类 号：Q6691[生物学—生物物理学]