大肠癌内分泌细胞免疫细胞化学研究  

IMMUNOCYTOCHEMICAL STUDY OF ENDOCRINE CELL IN CARCINOMAS OF THE LARGE INTESTINE

作　　者：韩玉祯 郑国均[1] 吴照敏[1] 

机构地区：[1]滨洲医学院病理学教研室

出　　处：《滨州医学院学报》1992年第4期292-293,381,共2页Journal of Binzhou Medical University

摘　　要：应用嗜银染色法和高血糖素及人绒毛膜促性腺激素(hCG)免疫细胞化学方法对47例普通型大肠癌进行研究,结果表明:47例大肠癌有5例呈嗜银反应阳性,其中仅1例呈高血糖素阳性反应。与正常大肠粘膜相比,大肠癌的高血糖素阳性率明显降低,且随其分化程度降低而阳性率逐渐降低。19例正常大肠粘膜 hCG 均呈阴性,大肠癌的 hCG 阳性率为40.4%,而不同组织类型和肿瘤分期之间无明显差异。In a series of 47 cases of adenocarcinomas of the large intestine,argyrophil cells were detected in 5 cases(10.6%) by argyrophil staining.Among the 5 cases,only one case was found positive for glucagon.The glucagon positive rate of the adenocarcinomas were lower than that of the mucosa of the large intestine,and the positive rate decreased with the degree of differ- entiation.19 cases of the normal mucosa were not found positive for hCG.The hCG positive rate of carcinomas was 40.4 %,and no significant differences were found between the different histo- logical types and the stages of the tumor.

关 键 词：嗜银染色法 高血糖素 大肠肿瘤 

分 类 号：R735.340.2[医药卫生—肿瘤]