产后抑郁症患者血清雌激素和孕激素水平的变化  

The changes of serum estradiol and progesterone concentrations in patients with postpartum depression

作　　者：何新红[1] 刘津予 李曦[1] 

机构地区：[1]河南省新乡医学院二附院,453002 [2]河南省新乡市第二人民医院,453002

出　　处：《广西医学》2002年第12期1928-1930,共3页Guangxi Medical Journal

摘　　要：目的 :探讨产后抑郁症的发生率及内分泌变化。方法 :用抑郁自评量表和焦虑自评量表分别评定 2 2 0例产妇的抑郁和焦虑情绪 ,用酶免法测定产妇的血清雌二醇和孕酮的含量。结果 :2 2 0例产妇抑郁情绪的发生率为 11.82 % ,焦虑情绪的发生率为 14 .0 9% ;产后抑郁症的产妇产前血清雌二醇和孕酮与无产后抑郁症的产妇相比无显著差异 ,产后前者雌二醇和孕酮显著低于后者。结论Objective:To observe the prevalence rate of postpartum depression and to study the changes of serum estradiol and progesterone concentrations in patients with postpartum depression Methods:Depress affection and anxious affection were measured in 220 postpartum women by Self Rating Depression Scale and Self Rating Anxiety Scale Serum estradiol and progesterone concentrations in postpartum women were measured by ELISA Results:The prevalence rate of depress affection was 11 82% and that of anxious affection was 14 09% There was not significant deference in serum estradiol and progesterone concentrations of antepartum between women with postpartum depression and women without postpartum depression Women with postpartum depression had significantly lower estradiol and progesterone concentrations of postpartum than women without depression Conclusion:The lower serum estradiol and progesterone concentrations may become one of etiologies of postpartum depression

关 键 词：产后抑郁症 雌二醇 孕酮 抑郁自评量表 焦虑自评量表 

分 类 号：R749.41[医药卫生—神经病学与精神病学]