2型糖尿病肾病患者凝血四项与血脂检测的意义  

The significance of four blood clotting items and blood lipid detection in patients with type 2 diabetic nephropathy

作　　者：祁晓婷[1] 单新洁 王昌敏[1] Qi Xiaoting;Shan Xinjie;Wang Changmin(The Clinical Laboratory Center of People's Hospital of Xinjiang Uygur Autonomous Region,Urumqi,Xinjiang,830001China;The Laboratory Department of Children's Hospital of Xinjiang Uygur Autonomous Region,Urumqi,Xinjiang,830054China)

机构地区：[1]新疆维吾尔自治区人民医院临检中心,新疆乌鲁木齐830001 [2]新疆维吾尔自治区儿童医院检验科,新疆乌鲁木齐830054

出　　处：《当代医学》2019年第24期106-107,共2页Contemporary Medicine

摘　　要：目的探究2型糖尿病肾病患者凝血四项与血脂检测的意义。方法研究对象为本院2016年6月至2017年6月收治的120例2型糖尿病肾病患者与50例健康体检者,对120例2型糖尿病肾病患者进行微量白蛋白检测后,依据检验结果将此120例患者进行分组,33例正常蛋白尿患者为A组(微量白蛋白<30 mg/24 h),49例微量白蛋白尿患者为B组(微量白蛋白30~300 mg/24 h),38例蛋白尿患者为C组(微量白蛋白>300 mg/24 h),50例健康体检者为对照组。对此4组进行空腹血糖(FBG)、活化部分凝血酶时间(APTT)、凝血酶时间(TT)、甘油三酯(TG)、纤维蛋白原(FIB)、凝血酶原时间(PT)检测,探讨2型糖尿病肾病患者凝血四项与血脂检测的意义。结果A、B、C 3组在TG、FBG、FIB、TT上与对照组相比,差异有统计学意义(P<0.05),在FIB、TT上,C组显著比A、B组高(P<0.05)。结论2型糖尿病在发生早期肾病时,患者血脂与凝血功能发生显著变化,FIB、TT明显升高,临床应针对此点,做好早期预防与治疗工作。Objective To discuss the significance of four blood clotting items and blood lipid detection in patients with type 2 diabetic nephropathy.Methods The subjects were 120 patients with type 2 diabetic nephropathy and 50 healthy subjects admitted to our hospital from June 2016 to June 2017,the microalbuminuria was detected in 120 patients with type 2 diabetic nephropathy,the 120 patients were grouped according to the results of the test,33 cases of normal proteinuria were group A(microalbumin<30 mg/24 h),49 cases of microalbuminuria were group B(microalbuminuria 30-300 mg/24 h),38 cases of proteinuria were C group(microalbumin>300 mg/24 h),50 cases of healthy physical examination as control group,the four groups were tested for fasting blood glucose(FBG),activated partial thromboplastin time(APTT),thrombin time(TT),triglyceride(TG),fibrinogen(FIB)and prothrombin time(PT),discussed the significance of four blood clotting items and blood lipid detection in patients with type 2 diabetic nephropathy.Results The three groups of A,B and C were significantly higher in TG,FBG,FIB and TT than those in the control group(P<0.05).On FIB and TT,C group was significantly higher than group A and B(P<0.05).Conclusion Patients with type 2 diabetes have significant changes in blood lipid and blood coagulation in early stage of kidney disease,FIB and TT are obviously increased,the early prevention and treatment work should be done for this point.

关 键 词：2型糖尿病肾病 凝血四项 血脂 检测意义 

分 类 号：R[医药卫生]