健脾和胃行气法治疗结肠癌术后辅助化疗引起的相关性不良反应的临床观察  

Clinical Study of the Efficacy of Strengthening the Spleen and Stomach and Promoting the Circulation on Improving Adverse Effect Caused by Colon Cancer Postoperative Adjuvant Chemotherapy

作　　者：郝晶[1] 朱伟[1] 董涵之[1] HAO Jing;ZHU Wei;DONG Hanzhi(Jiangxi Cancer Hospital,Nanchang,330029)

机构地区：[1]江西省肿瘤医院

出　　处：《实用癌症杂志》2019年第9期1526-1528,共3页The Practical Journal of Cancer

摘　　要：目的探讨健脾和胃行气法对结肠癌术后辅助化疗引起的相关性不良反应的疗效。方法采用随机对照研究方法将60例Ⅲ期结肠癌患者分为2组,实验组(30例)用中药配合化疗治疗,对照组(30例)单纯用化疗治疗。观察2组患者消化道不良反应以及血常规、电解质的变化。结果经3个月治疗后,对照组生活质量评分明显下降,治疗前后比较差异有统计学意义;实验组患者生活质量评分虽然下降,但治疗前后比较差异无统计学意义。实验组患者血常规白细胞、血红蛋白、血小板,电解质Na、K、Ca比同期对照组下降幅度小,有统计学意义。结论健脾和胃行气法对改善结肠癌术后辅助化疗引起的化疗相关性不良反应有一定疗效。Objective To study the efficacy of strengthening the spleen and stomach and promoting the circulation on improving adverse effect caused by Colon cancer postoperative adjuvant chemotherapy.Methods 60 patients with stageⅢcolon cancer using randomized controlled methods were divided into 2 groups:the experimental group(30 cases)treated with traditional Chinese medicine(TCM)combined with chemotherapy,the control group(30 cases)treated with chemotherapy alone.To observe the improvement of gastrointestinal adverse effect,blood routine and electrolyte changes in the two groups.Results After 3 months treatment,the quality of life score of the control group decreased significantly,and the difference before and after treatment was statistically significant.Although the quality of life score of patients in the experimental group decreased,There was no statistically significant difference before and after treatment.The leukocyte,hemoglobin,platelet,Na,K,Ca in the experimental group decreased less than that of the control group,there had significant statistical difference.Conclusion Strengthening the spleen and stomach and promoting the circulation is effective in improving the chemotherapy-related adverse effect induced by Colon cancer postoperative adjuvant chemotherapy.

关 键 词：健脾和胃行气 结肠癌 化疗 不良反应 生活质量 

分 类 号：R735.35[医药卫生—肿瘤]