CMU/1和CMU/2近交系长爪沙鼠脏器系数的比较  

Comparison of the Viscera Coefficient of CMU/1 and CMU/2 Inbred Strains of Gerbil

作　　者：马兰芝 李迎 尚世臣 黄斌 尚玉璞 王冬平 陈振文[2] MA Lanzhi;LI Ying;SHANG Shichen;HUANG Bin;SHANG Yupu;WANG Dongping;CHEN Zhenwen(Academy of Military Medicine Laboratory Animal Center of the Academy,Beijing 100071,China;Department of Laboratory Animal Science,Capital University Medical of Medical Sciences,Beijing 100069,China;College of Animal Science and Technology,Jilin Agricultural University,Changchun 130118,China)

机构地区：[1]军事医学研究院实验动物中心,北京100071 [2]首都医科大学实验动物科学部,北京100069 [3]吉林农业大学动物科学技术学院,长春130118

出　　处：《实验动物科学》2019年第4期60-62,67,共4页Laboratory Animal Science

基　　金：国家科技支撑计划课题(No.2015BAI09B01-04)

摘　　要：目的对近交系CMU/1和CMU/2长爪沙鼠的体质量和主要脏器质量进行测定,探索与建立长爪沙鼠主要脏器的生物学指标体系,为动物实验提供必要参数。方法选择3~4月龄近交系长爪沙鼠,分别称体质量与脏器质量,进行统计学分析。结果CMU/1和CMU/2近交系长爪沙鼠的肺脏器系数差异显著,其它差异不显著;Kendall和谐系数(W)接近1,其主要器官整体发育协调性较好;直线回归方程,CMU/1的胸腺P<0.05,CMU/2的肝、肺P<0.05,两样本间有线性关系。其中CMU/1的肝、脾、肾上腺、卵巢、胰腺和CMU/2的胸腺与体质量呈正相关。结论CMU/1及CMU/2近交系长爪沙鼠脏器系数中肺脏器系数差异显著,基因型对近交系长爪沙鼠脏器系数无明显影响。Objective To determine the body weight and main organ weight of inbred CMU/1 and CMU/2 inbred Mongolian gerbils,and to explore and establish the biological index system of main organs of Mongolian gerbils.It provides the necessary parameters for animal experiments.Method The body weight and organ weight of the 3~4 month-old gerbil in the inbred line were analyzed statistically.Result The difference between lung coefficient CMU/1 and CMU/2 inbred gerbils significantly,other no significant difference;Kendall coefficient(W)close to 1,the main organs of the overall development of better coordination;linear regression equation,the CMU/1 P<0.05,CMU/2 in the liver,thymus,lung P<0.05,two of the sample had a linear relationship between.The thymus of the liver,spleen,adrenal gland,ovary,pancreas and CMU/2 of CMU/1 was positively correlated with body weight.Conclusion There is significant difference in lung organ coefficient between CMU/1 and CMU/2 inbred strains of gerbil,and there is no obvious influence on the organ coefficient of the gerbil in the inbred line.

关 键 词：长爪沙鼠 近交系 脏器系数 

分 类 号：R-33[医药卫生]