影响消化系统恶性肿瘤术后胃瘫预后的相关因素探讨  

Discussion on the relevant factors influencing the prognosis of postoperative gastroparesis syndrome of digestive system malignant tumor

作　　者：谭雅彬 周琴[2] 胡叶 杨莹[1] 冯宝约 左明焕[2] TAN Yabin;ZHOU Qin;HU Ye;YANG Ying;FENG Baoyue;ZUO Minghuan(Beijing University of Chinese Medicine,Beijing100029,China;Department of Oncology,Dongfang Hospital of Beijing University of Chinese Medicine Beijing100078,China;Department of Oncology,Beijing Electric Power Hospital of State Grid Corporation of China,Beijing100073,China)

机构地区：[1]北京中医药大学,北京100029 [2]北京中医药大学东方医院肿瘤科,北京100078 [3]国家电网公司北京电力医院肿瘤科,北京100073

出　　处：《中国医药导报》2019年第23期98-101,共4页China Medical Herald

基　　金：国家自然科学基金资助项目(81373832)

摘　　要：目的探讨消化系统恶性肿瘤术后胃瘫综合征(PGS)预后的影响因素。方法选取北京中医药大学东方医院、中国医学科学院肿瘤医院、解放军总医院和北京大学人民医院4家三级甲等医院2013年1月~2015年12月收治的91例消化系统恶性肿瘤术后PGS患者进行临床回顾性分析。将消化系统恶性肿瘤术后PGS患者7 d以内(包括7 d)达到预后良好标准的51例患者作为观察组;14 d(包括14 d)仍未达到PGS预后良好标准的40例患者为对照组。采用单因素χ2检验和t检验分析13个可能影响消化系统恶性肿瘤术后PGS预后的相关因素。结果两组患者年龄、性别、体重指数、肿瘤转移、留置鼻胃管、营养支持方式、入组前3 d血清白蛋白量、高血压、冠心病、糖尿病指标差异无统计学意义(P> 0.05)。观察组患者入组前3 d血红蛋白量高于对照组,入组前3 d平均胃管引流量明显低于对照组,差异有统计学意义(P <0.05)。结论改善消化系统恶性肿瘤术后PGS患者的血红蛋白水平,控制胃管引流量,可能对改善患者的预后产生积极影响,对临床治疗具有参考意义。Objective To explore the influencing factors of prognosis of postoperative gastroparesis syndrome(PGS)in patients with digestive system malignant tumor.Methods A clinical retrospective analysis was conducted on 91 patients with PGS of digestive system malignant tumor treated in four grade A tertiary hospitals,namely,Dongfang Hospital of Beijing University of Chinese Medicine,Cancer Hospital of Chinese Academy of Medical Sciences,Chinese PLA General Hospital and Peking University People′s Hospital from January 2013 to December 2015.51 cases of patients with PGS of digestive system malignant tumor who achieved the favorable prognosis criteria within 7 days(7 day included)were selected as observation group;and 40 cases of patients failed in reaching the favorable prognosis of gastroparesis syndrome within 14 days(14 day included)were regarded as control group.13 relevant factors that may influence the prognosis of PGS of digestive system malignant tumor were analyzed by the adoption of single factor chi-square test and t test.Results There were no statistically significant differences in terms of patients′age,gender,body mass index,tumor metastasis,the placement of nasogastric tube,patterns of nutrition support,serum albumin amounts three days before admitting,hypertension,coronary heart disease and diabetes(P>0.05).The hemoglobin content 3 day before admitting in the observation group was higher than that of control group,the mean gastric tube drainage 3 day before admitting in the observation group was significantly lower than that of control group,the differences were statistically significant(P<0.05).Conclusion The improvement on hemoglobin levels and the control of the gastric tube drainage in patients with PGS of digestive system malignant tumor may exert a positive effect on the improvement of patients′ prognosis and have a referential significance to the clinical treatment.

关 键 词：消化系统恶性肿瘤术后胃瘫综合征 相关因素 预后 

分 类 号：R73.31[医药卫生—肿瘤]