生态免疫肠内营养支持对重症急性胰腺炎病人肝功能和预后影响  

Effect of ecological immune enteral nutrition support on prognosis and liver function of patients with severe acute pancreatitis

作　　者：王庆华 王凤[2] 逄泽辉 陈强谱[2] 成雨[2] 曲桂武 管清海[2] WANG Qinghua;WANG Feng;PANG Zehui;CHEN Qiangpu;CHENG Yu;QU Guiwu;GUAN Qinghai(Department of Nursing Humanity,Binzhou Medical University,Yantai 264003,P.R.China;Department of Hepatobiliary Surgery,Binzhou Medical University Hospital)

机构地区：[1]滨州医学院护理学院护理学人文教研室,烟台264003 [2]滨州医学院附属医院肝胆外科

出　　处：《滨州医学院学报》2019年第4期257-259,306,共4页Journal of Binzhou Medical University

基　　金：山东省自然科学基金项目(ZR2016HM26);山东省自然科学基金项目(ZR2016HL55)

摘　　要：目的探讨生态免疫肠内营养支持对重症急性胰腺炎(SAP)病人肝功能和预后影响。方法采用随机数字表法将64例SAP病人随机分为生态免疫肠内营养(EIEN)支持组和普通肠内营养(EN)支持组各32例,观察两组病人不同时间段肝功能变化和对预后影响。结果两组SAP病人治疗3 d、8 d后分别检测血白细胞计数、肝功能(谷丙转氨酶、谷草转氨酶、谷氨酰转肽酶)和治疗效果,两组指标比较具有统计学意义(P<0.05)。结论生态免疫肠内营养支持作为治疗重症急性胰腺炎(SAP)的治疗措施,具有保护肝脏功能、减少并发症发生和提高病人预后。Objective To study the effect of ecological immunity enteral nutrition on prognosis effect and liver function in the severe acute pancreatitis(SAP)patients.Methods The 58 patients with severe acute pancreatitis were randomized to ecological immunity enteral nutrition(EIEN group)64 and enteral nutrition(EN group)32 respectively.The changes of prognosis effect and liver function in both groups before and post nutrition support in 3 days and 8 days was determined.Results The white blood cell count,liver function(AST,ALT,γ-GT)and therapeutic effects of two groups of SAP patients were detected in the 3th days and 8th days after EIEN nutrition support.The two groups were statistically significant(P<0.05).Conclusion Ecological immunity enteral nutrition can protect liver function and reduce the SAP complications and enhanced treatment effect in the SAP patients,it was one of the important treatment methods for SAP patients and would be used widely in the practice.

关 键 词：生态免疫肠内营养支持 重症急性胰腺炎 肝功能 治疗效果 

分 类 号：R576[医药卫生—消化系统]