番茄红素对中枢神经系统保护机制研究进展  

Progress on the Protective Mechanisms of Lycopene on Central Nervous System

作　　者：杨艳 韦炎龙 方峰 YANG Yan;WEI Yan-Long;FANG Feng(State Key Laboratory of Bioreactor Engineering,East China University of Science and Technology,Shanghai 200237,China;Medical College of Luoyang Vocational and Technical College,Luoyang 471000,China)

机构地区：[1]华东理工大学生物反应器工程国家重点实验室,上海200237 [2]洛阳职业技术学院医学院,河南洛阳471000

出　　处：《生物技术通讯》2019年第4期560-566,共7页Letters in Biotechnology

基　　金：国家重点基础研究发展计划(2011CBA00800);国家自然科学基金(81373286)

摘　　要：番茄红素是一种天然的脂肪烃类胡萝卜素,广泛分布于番茄、木瓜和西瓜中,对一些中枢神经系统性疾病,如阿尔茨海默病、帕金森病、癫痫和抑郁症有预防或治疗作用,还能改善不同原因引起的认知和记忆障碍,预防三甲基锡等物质引起的神经毒性。本文综述了番茄红素预防或治疗中枢神经系统性疾病的机制。Lycopene is a natural fatty hydrocarbon carotene widely distributed in tomato,papaya and watermelon.It can prevent or treat some central nervous system diseases,such as Alzheimer's disease,Parkinson's disease,epilepsy and depression,improve cognitive and memory disorders caused by different reasons,and prevent neurotoxicity caused by monosodium glutamate,trimethyl tin and other substances.This article reviewed the mechanisms of lycopene in prevention and treatment of central nervous system diseases.

关 键 词：番茄红素 氧化应激 神经炎症 

分 类 号：Q25[生物学—细胞生物学]