运动神经元疾病患者的临床肌电图特征  

Clinical electromyographic characteristics of patients with motor neuron disease

作　　者：王兰琴 王琦 李薇 刘晓娜 龚爱平 WANG Lanqin;WANG Qi;LI Wei;LIU Xiaona;GONG Aiping(Department of Neurology,the Second Affiliated Hospital of Xuzhou Medical College,Xuzhou 221006,China)

机构地区：[1]徐州医科大学第二附属医院(徐州矿务集团总医院)神经内科

出　　处：《中国实用神经疾病杂志》2019年第15期1676-1681,共6页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨神经电生理肌电图检测在运动神经元疾病患者诊断中的价值。方法对20例确诊为运动神经元疾病的患者进行神经传导速度和针极肌电图检测与分析。结果广泛的神经源性损害普遍存在于运动神经元患者,部分患者发现插入电位延长,不同程度自发电位,其中纤颤电位15例(75.0%),正锐波13例(65.0%),束颤电位9例(45.0%),所有患者出现运动单位电位时限延长、波幅增高。5例(25.0%)运动神经传导速度显示轻度下降。结论神经电生理肌电图为运动神经元疾病的诊断及鉴别诊断提供了客观可靠的依据,对早期发现亚临床病变也有一定的意义。Objective To investigate the value of neuroelectrophysiological electromyographic test of patients with motor neuron disease(MND).Methods The nerve conduction velocity and needle electromyography were detected and analyzed in 20 patients diagnosed with motor neuron disease.Results Electromyography showed extensive neurogenic damage among all MND patients;the insertion potential was extended and spontaneous activity was increased with varying degrees in some MND patients;the incidence of fibrillation potential was 75.0%,positive wave 65.0%,fasciculation potential 45%;increased duration and amplitude of motor unit potential were present in all patients.Motion nerve conduction velocity showed mild decline in 5 MND patients.Conclusion The neuroelectrophysiological electromyographic test provides an objective and reliable basis for diagnosis and differential diagnosis of motor neuron disease,and has a certain significance in early detection of subclinical lesions.

关 键 词：运动神经元疾病 神经传导速度 肌电图 亚临床病变 

分 类 号：R744.8[医药卫生—神经病学与精神病学]