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机构地区:[1]Johns Hopkins University,Whiting School of Engineering,Institute for NanoBioTechnology,inHealth Measurement Corps,Baltimore,Maryland,USA [2]Institute for Prediction Technology,Department of Family Medicine,University of California,Los Angeles,California,USAUniversity of California,Los Angeles,California,USA
出 处:《Journal of Clinical & Translational Research》2018年第3期7-10,共4页临床和转化研究
摘 要:Although strict adherence to antiretroviral therapy(ART)lowers morbidity and mortality for people living with HIV and AIDS,there are a number of behavioral,cultural,and psychosocial factors that prevent people from adhering to their medication[1].Within African-American and Latino communities,for example,stigma around sexual identity and behavior hinders open dialogue about the value and proper use of HIV treatment medications[2,3].In addition,misunderstandings about how ART affects the body have led some patients to believe that they can skip doses without experiencing negative consequences.For example,in 2015,the actor Charlie Sheen—who has been influential in raising public awareness about HIV—announced on The Dr.Oz Show that he has strayed from his ART regimen[4].As a result,public health researchers require innovative methods for monitoring and improving adherence to HIV and other medications.
关 键 词:INTESTINAL failure liver disease enterohepatic cycle BILE SALT signaling FXR enterocutaneous FISTULA
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