血清S-ChE LPO及血常规联合检测对老年重症肺炎预后的评估  

Evaluation of Prognosis of Severe Pneumonia by Serum S-ChE LPO Routine Blood

作　　者：巫太平 刘玲 WU Taiping;LIU Ling(Deyang Second People's Hospital,Sichuan Deyang 618000,China)

机构地区：[1]四川省德阳市第二人民医院检验科

出　　处：《河北医学》2019年第9期1459-1462,共4页Hebei Medicine

基　　金：四川省卫计委科研课题立项项目,(编号:150198)

摘　　要：目的:研究血清S-ChE、LPO及血常规联合检测对老年重症肺炎预后的评估价值。方法:选择2016年5月至2018年5月在我院接受治疗的重症肺炎老年患者175例,根据病情转归情况分为迁延恶化组75例,好转组100例,检测两组血清S-ChE、LPO及血常规(WBC、PLT)水平,采用ROC曲线下面积分析S-ChE、LPO及血常规检测对重症肺炎预后的评估价值。结果:恶化组血清S-ChE、LPO水平均明显高于好转组(P<0.05),两组血常规水平比较则无明显差异(P<0.05);经ROC曲线分析,S-ChE评估重症肺炎预后的ROC曲线下面积为0.857,敏感性75.34%、特异性79.39%、准确率78.29%,LPO评估曲线下面积为0.772,敏感性73.68%、特异性72.03%、准确率72.57%;血常规评估曲线下面积为0.643,敏感性51.92%、特异性60.98%、准确率58.29%,三者联合预测曲线下面积为0.913,敏感性81.58%、特异性86.87%、准确率84.57%,均高于单独预测,比较差异显著(P<0.05)。结论:老年重症肺炎预后与患者血清S-ChE、LPO水平变化有关,与血常规无明显的关系,三者联合评估其预后具有重要的临床意义。Objective:To study evaluation of prognosis of Severe Pneumonia by Serum S-ChE,LPO,Routine blood.Methods:175 patients of severe pneumonia who received therapy from May 2016 and May 2018 in our hospital were selected,According to the condition of the disease,it was divided into 75 cases of delayed deterioration group and 100 cases of improvement group.Serum S-ChE,LPO and blood routine(WBC,PLT)levels of the two groups were detected.Results:Serum s-ChE and LPO levels in the worsening group were higher than the improving group(P<0.05),but there was no significant difference between the two groups(P<0.05).According to ROC curve analysis,the area under the ROC curve of s-ChE in evaluating the prognosis of severe pneumonia was 0.857,with sensitivity of 75.34%,specificity of 79.39%,accuracy rate of 78.29%,evaluation curve area of LPO was 0.772,sensitivity of 73.68%,specificity of 72.03%and accuracy of 72.57%.Blood routine evaluation curve area was 0.643,sensitivity 51.92%,specificity of 60.98%,accuracy 58.29%,and the combined prediction curve area was 0.913,sensitivity 81.58%,specificity 86.87%and accuracy 84.57%,all of which were higher than individual prediction,with significant difference(P<0.05).Conclusion:The prognosis of severe pneumonia in the elderly is related to changes in serum S-ChE and LPO levels of patients,and has no obvious relationship with blood routine.It is of great clinical significance to jointly evaluate the prognosis of severe pneumonia in the elderly.

关 键 词：重症肺炎 S-ChE LPO 

分 类 号：R73[医药卫生—肿瘤]