彩色多普勒超声在缺血性脑血管病患者颈动脉病变检测中的应用  

Application of color Doppler ultrasound in diagnosis of carotid lesion in patients with ischemic cerebrovascular disease

作　　者：沈文[1] 陈兰英[1] 张学林[2] 杨庆华[3] SHEN Wen;CHEN Lanying;ZHANG Xuelin(Department of Neurology,The Second Affiliated Hospital of Hebei North University,Hebei,Zhangjiakou 075100,China)

机构地区：[1]河北北方学院附属第二医院神经内科,河北省张家口市075100 [2]河北北方学院附属第二医院呼吸内科,河北省张家口市075100 [3]河北北方学院附属第二医院功能科,河北省张家口市075100

出　　处：《河北医药》2019年第19期2962-2964,2968,共4页Hebei Medical Journal

基　　金：张家口市科学技术研究与发展指导计划项目(编号:1221046D)

摘　　要：目的 探讨彩色多普勒超声在缺血性脑血管病(ICVD)患者颈动脉病变检测中的应用价值。方法 选取2015年9月至2017年3月收治的ICVD患者130例进行研究,依据颈动脉狭窄程度分为无狭窄组51例、轻度狭窄组37例、中度狭窄组27例、重度狭窄组15例,另选取同期健康体检者50例为对照组。采用彩色多普勒超声诊断仪测量颈总动脉、颈内动脉内径(VD)及血流动力学情况,包括收缩期最大血流速度(PSV)、舒张末期最低血流速度(EDV)、平均血流速度(MFV)、血管反应性(VR)、动脉内-中膜厚度(IMT)。结果 颈总动脉、颈内动脉无狭窄组,轻度狭窄组,中度狭窄组VD、IMT、PSV、EDV、MFV与对照组比较差异无统计学意义(P>0.05),重度狭窄组VD、IMT、PSV、EDV、MFV与对照组比较差异有统计学意义(P<0.05);无狭窄组、轻度狭窄组、中度狭窄组、重度狭窄组VR逐渐降低,与对照组比较差异有统计学意义(P<0.05)。结论 颈动脉粥样硬化(CAS)与ICVD关系密切,彩色多普勒超声检测颈动脉血流动力学参数改变,有助于IVCD的早期诊断,了解病变程度,指导临床用药。Objective To investigate the application value of color Doppler ultrasound in diagnosis of carotid lesion in patients with ischemic cerebrovascular disease(ICVD).Methods A total of 130 patients with ICVD who were admitted and treated in our hospital from September 2015 to March 2017 were enrolled in the study,who were divided into no stenosis group(n=51),mild stenosis group(n=37),moderate stenosis group(n=27),and severe stenosis group(n=15)according to the carotid artery stenosis degree.Moreover,50 healthy subjects who underwent physical examinations at the same period were served as control group.The color Doppler ultrasound diagnostic apparatus was used to measure the VD,PSV,EDV,MFV,VR and IMT.Results There were no significant differences in VD,IMT,PSV,EDV,and MFV between the three stenosis groups and control group(P>0.05).However there were significant differences in VD,IMT,PSV,EDV,and MFV between severe stenosis group and control group(P<0.05).Moreover the VR in no stenosis group,mild stenosis group,moderate stenosis group and severe stenosis group was gradually decreased,which was significantly different from that in control group(P<0.05).Conclusion The carotid atherosclerosis(CAS)is closely correlated with ICVD.The detection of carotid hemodynamic parameters change by color Doppler ultrasound is helpful for the early diagnosis of IVCD,understand the lesion degree,and guiding clinical medication.

关 键 词：彩色多普勒超声 缺血性脑血管病 颈动脉粥样硬化 血流动力学 

分 类 号：R743[医药卫生—神经病学与精神病学]