我国血液肿瘤移植治疗的发展与现状  

Advances and current status of stem cell transplantation in treatment of hematological malignancies in China

作　　者：常英军[1] Chang Yingjun(Peking University People's Hospital&Peking University Institute of Hematology,National Clinical Research Center for Hematologic Disease,Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation,Beijing 100044,China)

机构地区：[1]北京大学人民医院,北京大学血液病研究所,国家血液系统疾病临床医学研究中心,造血干细胞移植治疗血液病北京市重点实验室,100044

出　　处：《白血病．淋巴瘤》2019年第8期485-489,共5页Journal of Leukemia & Lymphoma

摘　　要：新中国成立以来,我国学者从完成首例同基因骨髓移植到建立国际原创的非体外去除T细胞的单倍型相合骨髓和外周血混合移植体系(被称为"北京方案"),实现了造血干细胞移植从"跟跑"到"领跑"的转变,基本解决了供者来源问题.文章综述了我国血液肿瘤移植治疗的发展现状和需要应对的挑战.Since the founding of the People's Republic of China, much progress has been made in the field of stem cell transplantation by Chinese scholars. From the successful treatment of the first case with syngeneic bone marrow transplantation to the international original establishment of T-cell-replete haploidentical blood and marrow transplant system (known as the "Beijing Protocol"). The transformation of hematopoietic stem cell transplantation from "follow-up" to "lead-up" has been realized, and the problem of donor source has been basically solved. This article summarized the development status of stem cell transplantation in treatment of hematological malignancies in China, and the challenges that need to be addressed.

关 键 词：血液肿瘤 造血干细胞移植 异基因 单倍型相合移植 

分 类 号：R73[医药卫生—肿瘤]