核酸代谢与营养研究及发展趋势  

Researches on Nucleic Acid Metabolism and Nutrition and Their Development

作　　者：梁兴国[1,2] 李佥 黄丽丽 刘艺璇 董平 LIANG Xing-Guo;LI Qian;HUANG Li-Li;Liu Yi-Xuan;DONG Ping(College of Food Science and Engineering,Ocean University of China,Qingdao 266003,China;Laboratory for Marine Drugs and Bioproducts,Qingdao National Laboratory for Marine Science and Technology,Qingdao 266235,China)

机构地区：[1]中国海洋大学食品科学与工程学院,山东青岛266003 [2]青岛海洋科学与技术国家实验室海洋药物与生物制品功能实验室,山东青岛266235

出　　处：《中国海洋大学学报（自然科学版）》2019年第10期64-78,共15页Periodical of Ocean University of China

基　　金：国家自然科学基金项目（31741099）;山东省自然科学基金项目（ZR2017MC012）;中央高校基本科研业务费专项（201812009）资助~~

摘　　要：核酸类物质(NAS)因具有遗传、介导和催化生化反应、提供或转移能量等多种生物功能,被认为是生物体内极其重要的一类分子。但对于NAS(包括核苷酸、核酸及其衍生物)是否具有营养功能的问题一直存在争议,甚至几乎所有营养学教科书都不涉及这一内容。本文在综述核酸营养研究的基础上,对相关研究的进展及发展趋势展开讨论,包括相关研究的发展历程、理论基础、应用、争议问题以及NAS对其他生物的营养价值等内容。NAS是“条件型营养物质”,对高等动物的生长、新陈代谢、免疫、肠和肝脏等器官的更新或修复等发挥着重要作用;NAS已在功能食品和饲料添加剂等产业得到广泛应用。期待更多的科研工作者对核酸营养研究产生兴趣,开展相关研究,形成对核酸营养正确、系统的认识,以完善相应的营养学理论并对NAS进行合理利用。Nucleic acid substances(NAS)are considered to be an extremely important class of molecules in organisms because they function heredity,mediate and catalyze biochemical reactions,provide or transfer energy among others.However,whether NAS(including nucleotides,nucleic acids and their derivatives)have nutritional function has been controversial.Almost all nutrition textbooks do not cover this content.Based on the review of nucleic acid nutrition research,we discussed the progress and development trend of related researches,including the development process,theoretical basis,application,controversial issues and the nutritional value of NAS to other organisms.NAS are conditional nutrients,which play important roles in the growth,metabolism,immunity,intestinal and liver organ renewal of higher animals.NAS have been widely used in functional food and feed additives industries.It is expected that more scientific researchers will be interested in the studies of nucleic acid nutrition and carry out relevant researches to form a correct and systematic understanding of nucleic acid nutrition,so as to improve the relevant nutritional theory and make rational use of NAS.

关 键 词：核苷酸 核酸 核酸营养 核酸代谢 饲料添加剂 

分 类 号：TS201.4[轻工技术与工程—食品科学]