丙氨酰谷氨酰胺氨基酸(18)注射液对术后食管癌患者的疗效研究  

Study on Curative Effect of Alanyl Glutamine Amino Acid(18) Injection on Patients with Esophageal Cancer after Surgery

作　　者：祁雯 柯有力[1] QI Wen;KE Youli(Department of Thoracic and Vascular Surgery,Wuhan First Hospital,Wuhan 430022,China)

机构地区：[1]武汉市第一医院普胸血管外科

出　　处：《临床医学工程》2019年第9期1235-1236,共2页Clinical Medicine & Engineering

摘　　要：目的探讨丙氨酰谷氨酰胺氨基酸(18)注射液对术后食管癌患者预后的影响。方法选取我院2016年9月至2018年12月收治的46例食管癌患者,随机将其分为观察组[常规治疗+丙氨酰谷氨酰胺氨基酸(18)注射液]与对照组(常规治疗),各23例。对比两组患者治疗前后Gal-3、D-二聚体、COX-2水平及治疗总有效率。结果治疗前,两组的Gal-3、D-二聚体、COX-2水平比较无统计学差异(P>0.05);治疗后,观察组的Gal-3、D-二聚体、COX-2水平均低于对照组(P<0.05)。观察组的治疗总有效率显著高于对照组(P<0.05)。结论丙氨酰谷氨酰胺氨基酸(18)注射液能够有效改善患者的营养状况,提升治疗效果。Objective To study the influence of alanyl glutamine amino acid(18)injection on the prognosis of patients with esophageal cancer after surgery.Methods 46 cases of patients with esophageal cancer admitted to our hospital from September 2016 to December 2018 were selected and randomly divided into observation group[routine treatment+alanyl glutamine amino acid(18)injection]and control group(routine treatment),with 23 cases in each group.The Gal-3,D-dimer and COX-2 levels before and after treatment,and total effective rate were compared between the two groups.Results Before treatment,no statistical difference was found in the Gal-3,D-dimer and COX-2 levels between the two groups(P>0.05).After treatment,the Gal-3,D-dimer and COX-2 levels of the observation group were lower than those of the control group(P<0.05).The total effective rate of treatment in the observation group was significantly higher than that in the control group(P<0.05).Conclusions Alanyl glutamine amino acid(18)injection can effectively improve the nutritional status of patients,and improve the treatment effect.

关 键 词：丙氨酰谷氨酰胺氨基酸 食管癌 疗效 

分 类 号：R735.1[医药卫生—肿瘤]