肠道微生物在炎症性肠病发病机制中的作用  

Role of Gut Microbiota in Pathogenesis of Inflammatory Bowel Disease

作　　者：刘海燕[1] 刘婷[1] LIU Hai-yan;LIU Ting(The Hospital of PLA 82st Group Army,Baoding,Hebei 071000,China)

机构地区：[1]中国人民解放军第八十二集团军医院

出　　处：《河北北方学院学报（自然科学版）》2019年第10期47-50,共4页Journal of Hebei North University:Natural Science Edition

摘　　要：肠道微生物在抵抗疾病,维持人体健康和能量平衡方面具有重要作用。炎症性肠病(inflammatory bowel disease,IBD)发病过程中肠道微生物数量和结构都有所改变,导致机体生态失衡。个体敏感性,环境因素如营养、用药、年龄以及吸烟都可改变肠道微生物菌群,进而引发IBD。对肠道微生物在IBD发病机制中的作用进行综述。Gut microbiota plays an important role in resisting diseases and maintaining human health and energy balance.The quantity and structure of gut microbiota have changed during the pathogenesis of inflammatory bowel disease(IBD),leading to ecological imbalance.Individual sensitivity and environmental triggers such as nutrition,medication,age and smoking can alter intestinal microflora,which can lead to IBD.The role of gut microbiota in the pathogenesis of IBD was reviewed.

关 键 词：炎症性肠病 克罗恩病 溃疡性结肠炎 肠道微生物 粪菌移植 

分 类 号：R574[医药卫生—消化系统]