小脑发育不良性神经节细胞瘤的临床特征与MRI表现  

Clinical Features and MRI Manifestations of Lhermitte-Duclos Disease

作　　者：李贝贝[1] 任翠萍[1] 程敬亮[1] 李莹[1] 肖翠萍[1] 林晨[1] LI Beibei;REN Cuiping;CHENG Jingliang;LI Ying;XIAO Cuiping;LIN Chen(Department of MRI,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区：[1]郑州大学第一附属医院磁共振科

出　　处：《中国医学影像学杂志》2019年第9期646-648,共3页Chinese Journal of Medical Imaging

摘　　要：目的探讨小脑发育不良性神经节细胞瘤(LDD)的MRI特征性表现及临床特点。资料与方法回顾性分析5例经手术病理证实为LDD患者的临床资料及MRI表现,包括肿瘤发病部位、大小、形态及信号强度,同时记录是否伴有瘤周水肿、瘤体是否强化及强化方式等。结果5例LDD患者中,2例位于右侧小脑半球,1例累及右侧小脑半球及右侧桥小脑结合臂,1例位于左侧小脑半球,1例位于小脑上蚓部。瘤体内存在呈斜形或纵行排列的条片状结构,呈“虎斑征”;与正常脑组织对比呈层状等/长T1、等/长T2信号;5例均无明显瘤周水肿;3例增强扫描病灶未见明显强化,2例呈点条状轻度强化。结论LDD的MRI表现具有典型“虎斑征”,并有明显的占位效应。增强扫描病变不强化或轻微强化。Purpose To investigate the MRI manifestations and clinical features of Lhermitte-Duclos disease(LDD).Materials and Methods Clinical data and MRI manifestations of 5 patients with LDD confirmed by pathology were retrospectively analyzed,including the location,size,shape and signal intensity of the tumor,and recording whether the peri-tumoral edema,whether the tumor was strengthened and its strengthening method.Results For 5 cases with LDDs,the tumor was located in the right cerebellar hemisphere in 2 cases,in the right cerebellar hemisphere and right olivopontocerebellar brachium conjunctivum in 1 case,in the left cerebellar hemisphere in 1 case and in the superior vermis in 1 case.There were striped structures arranged in oblique line or longitudinal line in the tumor,showing“tiger spot signs”,which exhibited layered isometric T1 and isometric T2 signals compared with normal brain tissue.There was no obvious peri-tumoral edema in all 5 cases;no significant enhancement was found through enhancement scan in 3 cases,and dot-bar light enhancement was observed in 2 cases.Conclusion MRI manifestations of LDDs show typical“tiger spot signs”and a mass effect.Enhancement scan demonstrates that the lesion is not enhanced or slightly enhanced.

关 键 词：神经节瘤 小脑肿瘤 磁共振成像 疾病特征 病理学 外科 

分 类 号：R739.4[医药卫生—肿瘤] R445.2[医药卫生—临床医学]