Primary hypoparathyroidism accompanied by rhabdomyolysis induced by infection: A case report  

作　　者：Li-Na Ding Yi Wang Jun Tian Li-Fang Ye Shi Chen Shi-Min Wu Wen-Bin Shang 

机构地区：[1]Department of Endocrinology,the Affiliated Hospital of Nanjing University of Chinese Medicine,Jiangsu Provincial Hospital of Chinese Medicine,Nanjing 210029,Jiangsu Province,China [2]Department of General Surgery,Zhangjiagang Traditional Chinese Medicine Hospital affiliated with Nanjing University of Chinese Medicine,Zhangjiagang 215600,Jiangsu Province,China [3]Department of Gynecology and Obstetrics,Changshu Traditional Chinese Medicine Hospital affiliated with Nanjing University of Chinese Medicine,Changshu 215500,Jiangsu Province,China

出　　处：《World Journal of Clinical Cases》2019年第19期3111-3119,共9页世界临床病例杂志

摘　　要：BACKGROUND Primary hypoparathyroidism(HPT)is rarely seen in the clinic,and it can be combined with rhabdomyolysis.There are few reports about this phenomenon.Therefore,it is significant to explore the etiology that is conducive to early diagnosis,timely treatment,and preventing the recurrence.CASE SUMMARY A 63-year-old man was admitted to our hospital with a severe upper respiratory tract infection and progressing decreased myodynamia of the lower limbs.Blood tests showed creatine kinase>32000 U/L,creatinine 207.8μmol/L,calcium 1.28 mmol/L,myoglobin 558.7 ng/mL,and parathyroid hormone 0 pg/mL.He was diagnosed with primary HPT with rhabdomyolysis,and severe upper respiratory tract infection was considered to be the initial trigger.He responded well to supplementation of intravenous calcium gluconate and oral calcium as well as bedside hemodialysis,fluid hydration,infection control,protecting the liver,etc.Creatine kinase,myoglobin,and serum calcium returned to normal,and muscle strength improved significantly.Symptoms improved after symptomatic treatment.CONCLUSION Severe infection should be prevented,which is the key cause of rhabdomyolysis in patients with HPT.BACKGROUND Primary hypoparathyroidism(HPT) is rarely seen in the clinic, and it can be combined with rhabdomyolysis. There are few reports about this phenomenon.Therefore, it is significant to explore the etiology that is conducive to early diagnosis, timely treatment, and preventing the recurrence.CASE SUMMARY A 63-year-old man was admitted to our hospital with a severe upper respiratory tract infection and progressing decreased myodynamia of the lower limbs. Blood tests showed creatine kinase > 32000 U/L, creatinine 207.8 μmol/L, calcium 1.28 mmol/L, myoglobin 558.7 ng/mL, and parathyroid hormone 0 pg/mL. He was diagnosed with primary HPT with rhabdomyolysis, and severe upper respiratory tract infection was considered to be the initial trigger. He responded well to supplementation of intravenous calcium gluconate and oral calcium as well as bedside hemodialysis, fluid hydration, infection control, protecting the liver, etc.Creatine kinase, myoglobin, and serum calcium returned to normal, and muscle strength improved significantly. Symptoms improved after symptomatic treatment.CONCLUSION Severe infection should be prevented, which is the key cause of rhabdomyolysis in patients with HPT.

关 键 词：PRIMARY HYPOPARATHYROIDISM RHABDOMYOLYSIS HYPOCALCEMIA Decreased myodynamia Respiratory tract INFECTION Case report 

分 类 号：R73[医药卫生—肿瘤]