耳尖放血治疗早期麦粒肿的Meta分析  

Meta-analysis of Ear Tip Bloodletting For Early Hordeolum

作　　者：陈梦[1] 李滢[1] 周占宇[1] CHEN Meng;LIYing;ZHOU Zhan-yu(Department of Ophthalmology,Qingdao Municipal Hospital,Qingdao 266000,Shandong,China)

机构地区：[1]青岛市市立医院眼科

出　　处：《医学信息》2019年第21期72-77,共6页Journal of Medical Information

摘　　要：目的系统评价经耳尖放血治疗早期麦粒肿的临床疗效。方法检索中国学术期刊全文数据库(CNKI)、维普数据库(VIP)、万方数据库及PubMed数据库,收集建库至2018年12月18日所有耳尖放血治疗早期麦粒肿的随机对照试验(RCT)研究资料,通过Cochrane系统的偏倚风险评估工具对文献进行方法学质量评价,利用Revman5.3软件对其总有效率效应结局指标进行分析。结果共纳入文献13篇,合计1345例患者。Meta分析显示耳尖放血或联合其他常规药物治疗早期麦粒肿的总有效率优于常规药物疗法,差异有统计学意义[OR=5.14,95%CI(3.66,7.99),Z=8.46,P<0.00001],其中耳尖放血结合西药组效果优于西药组,差异有统计学意义[OR=5.00,95%CI(2.61,9.56),Z=4.86,P<0.00001];单纯耳尖放血组效果同样优于西药组,差异有统计学意义[OR=4.31,95%CI(1.41,13.21),Z=2.56,P=0.01]。结论耳尖放血单用或配合常规药物治疗早期麦粒肿优于常规药物疗法,但设计严谨、方法科学的高质量文献较少,其可靠性偏低,因此上述结果仍需要进一步验证。Objective To systematically evaluate the clinical efficacy of treatment of early hordeolumby ear tip bleeding.Methods Search the Chinese Academic Journal Full-text Database(CNKI),VIP Database(VIP),Wanfang Database and PubMed Database,and collect randomized controlled trials(RCT)data from all ear tip bloodletting treatments for early stigma on December 18,2018.The Cochrane system's bias risk assessment tool evaluated the methodological quality of the literature and analyzed its total effective effect outcomes using Revman 5.3 software.Results A total of 13 articles were included in the literature,totaling 1345 patients.Meta-analysis showed that the total effective rate of ear tip bleeding or other conventional drugs in the treatment of early hordeolum was superior to conventional drug therapy,the difference was statistically significant[OR=5.14,95%CI(3.66,7.99),Z=8.46,P<0.00001].The effect of bloodletting combined with western medicine group was better than that of western medicine group,the difference was statistically significant[OR=5.00,95%CI(2.61,9.56),Z=4.86,P<0.00001];the effect of simple ear tipping group was also better than western medicine,the difference was statistically significant[OR=4.31,95%CI(1.41,13.21),Z=2.56,P=0.01].Conclusion Ear bleed alone or in combination with conventional drugs for the treatment of early hordeolum is superior to conventional drug therapy,but the high-quality literature with strict design and scientific method is less,and its reliability is low.Therefore,the above results still need further verification.

关 键 词：耳尖穴 放血 麦粒肿 META分析 

分 类 号：R743.3[医药卫生—神经病学与精神病学]