玻璃酸钠联合氯替泼诺治疗儿童急性结膜炎后干眼的疗效观察  

Observation of sodium hyaluronate combined with loteprednol for treatment of children with acute conjunctivitis after the treatment of dry eye

作　　者：张立友[1] 陈忠飞[1] 韩二杰 庞彦英[1] Zhang Liyou;Chen Zhongfei;Han Erjie;Pang Yanying(Cangzhou Eye Hospital,Cangzhou,Hebei,061000)

机构地区：[1]沧州眼科医院

出　　处：《中医眼耳鼻喉杂志》2019年第2期93-95,共3页Journal of Chinese Ophthalmology and Otorhinolaryngology

摘　　要：目的观察玻璃酸钠联合氯替泼诺治疗儿童急性结膜炎后干眼的疗效。方法选取患急性结膜炎后经确诊的干眼儿童99例195眼,随机分为对照组与观察组。观察组49例(98眼)给予玻璃酸钠联合氯替泼诺治疗,对照组50例(97)给予玻璃酸钠点眼,治疗1mo后比较两组临床疗效。结果观察组有效率为95.91%,对照组82.47%,二者有统计学差异(P<0.05)。两组主观症状、泪膜破裂时间、泪河高度均较治疗前有明显改善,有统计学差异(P<0.05);两组均无不良反应出现。结论玻璃酸钠联合氯替泼诺治疗儿童急性结膜炎后干眼疗效较好,用药安全,无不良反应。Objective To observe the efficacy and safety of dry eye observation of sodium hyaluronate combined with loteprednol for treatment of children with acute conjunctivitis after.Methods Select suffering from acute conjunctivitis after the diagnosis of dry eye in children 195 cases of 99 eyes,were randomly divided into control group and observation group。The observation group of 49 cases(98 eyes)with sodium hyaluronate combined with Loteprednol treatment,the control group of 50 cases(97 eyes)with sodium hyaluronate after 1Mo treatment,compared two groups of clinical curative effect.Results The effective rate of the observation group was 95.91%,82.47%in the control group,the difference was statistically significant(<0.05).two groups of subjective symptoms,tear break-up time,tear meniscus height were significantly improved compared with before treatment,there was significant difference(P<0.05);There were no adverse reactions in the two groups.Conclusion Sodium hyaluronate combined with loteprednol for treatment of children with acute conjunctivitis after dry eye good curative effect,medication safety,no adverse reaction.

关 键 词：玻璃酸钠 氯替泼诺 儿童 急性结膜炎 干眼 

分 类 号：R77[医药卫生—眼科]