广西甜茶醇提物对小鼠血糖及糖耐量的影响  

Effects of ethanol extract of Rubus suavissimus S. Lee on blood sugar and glucose tolerance in mice

作　　者：蒙淑洁 闫志刚[2] 徐永莉[2] 吴庆华[2] 冯世鑫[2] 李力[1,2] MENG Shu-jie;YAN Zhi-gang;XU Yong-li;WU Qing-hua;FENG Shi-xin;LI Li(Guangxi Medical University,Nanning 530021,China;Guangxi Botanical Garden of Medicinal Plants,Nanning 530023,China)

机构地区：[1]广西医科大学,南宁530021 [2]广西药用植物园,南宁530023

出　　处：《湖北农业科学》2019年第20期118-120,共3页Hubei Agricultural Sciences

基　　金：广西重点研发计划项目（桂科AB16380346）;2015年生态广西建设引导资金项目[桂财建函（2015）87号文]

摘　　要：为研究广西甜茶(Rubus suavissimus S.Lee)醇提物对小鼠血糖及糖耐量的影响,分为空白组、广西甜茶醇提物高、中、低(250、150、100 g/kg)等4组剂量组,对小鼠连续灌胃给药40 d,观察其对小鼠血糖的影响。结果表明,广西甜茶醇提物低剂量组(P<0.01)和中剂量组(P<0.05)对小鼠空腹血糖有显著影响,并随着给药时间的延长,对葡萄糖致小鼠高血糖有一定的抑制作用,与空白对照组相比低剂量组和中剂量组给药40 d后体重明显降低。To study the effects of ethanol extract of Rubus Suavissimus S.Lee on blood sugar and glucose tolerance in mice.KM mice were divided into four dosage groups:blank group,high,medium and low ethanol extracts of sweet tea from Rubus suavissimus S.Lee(250,150,100 g/kg).The effects of ethanol extracts on blood sugar in normal mice were observed after 40 days of continuous intragastric administration.The results showed that low-dose group(P<0.01)and middle-dose group(P<0.05)of ethanol extract of Rubus suavissimus S.Lee had significant effects on fasting blood glucose in mice,and with the increase of administration time,they had certain inhibitory effects on hyperglycemia induced by glucose in mice.Compared with the blank control group,the body weight of low-dose group and middle-dose group after 40 days of administration was significant markedly reduced.

关 键 词：广西甜茶(Rubus suavissimus S.Lee) 醇提物 空腹血糖 糖耐量 体重 

分 类 号：S571.1[农业科学—茶叶生产加工] O622.3[农业科学—作物学]