健康体检人群结直肠息肉患病情况及临床特征  

Prevalence and clinical features of colorectal polyps in health examination population

作　　者：刘宇英[1] 伍民庆[1] 李艳红[1] 谢传波 严岳[1] LIU Yuying;WU Minqing;LI Yanhong;XIE Chuanbo;YAN Yue(Department of Cancer Prevention Sun Yat Sen University Cancer Center,Guangzhou 510060,China)

机构地区：[1]中山大学肿瘤防治中心防癌体检健康管理中心华南肿瘤学国家重点实验室肿瘤医学协同创新中心

出　　处：《实用医学杂志》2019年第20期3239-3242,共4页The Journal of Practical Medicine

基　　金：广东省医学科学技术研究基金项目(编号：201802693158611)

摘　　要：目的研究健康人群中结直肠息肉的患病情况及临床特征。方法回顾分析2014年1月至2017年12月在中山大学附属肿瘤医院防癌体检健康管理中心进行电子结肠镜健康体检的6 723例体检结果,纳入拥有完整临床资料的受检者共3 607例,分析健康体检人群中结直肠疾病的发病情况。发现结直肠息肉共1 165例,分为息肉组,结肠镜未发现明确异常共2 323例,分为正常组。研究息肉组不同年龄段的息肉检出率,结直肠癌检出率,临床、病理特征。最后对比息肉组和正常组之间的临床资料差别。结果发现结直肠息肉共1 165例,肠粘膜炎症共108例,肠憩室共27例,大肠黑变病共14例,结直肠恶性肿瘤共8例,肠粘膜淋巴滤泡增生共19例,肠镜未见明确异常共2 323例。息肉组中男性例数多于女性,单发组例数多于多发组,左半结肠息肉例数高于右半结肠,管状腺瘤例数高于其他病理类型。息肉组和正常组对比发现50岁以上组的肠息肉检出率高于50岁以下组,男性组肠息肉检出率高于女性组,BMI≥24组息肉检出率高于BMI<24 kg/m2组。结论健康体检人群当中,男性、BMI≥24 kg/m^2、50岁以上的人群、左半结肠应该为肠镜筛查的重点。Objective To find the prevalence and clinical features of colorectal polyps in health examina tion population.Methods Based on retrospective analysis of a population of 6 723 people with colonoscopy screen ing in health examination in cancer prevention center of Sun Yat Sen University Cancer Center from Jan 2014 to Dec 2017,the incidence of anal disease and colon disease was analyzed.A total of 1 165 people with colorectal polyps detected were involoved in polyp group and 2 323 people without in normal group.Detection rate of polyp and colorectal cancer and clinical and pathological features were compared in the two groups.Results Colorectal polyp was found in 1 165 people and there were 108 cases of intestinal mucosal inflammation,27 cases of diverticular disease,14 of melanosis coli,8 of colorectal cancer,and 19 cases of lymphoid follicular hyperplasia of intestine mucous membrane.There was no abnormality in 2 323 objects.In polyp group,there were more males,more single polyps and more polyps in the left hemicolon and the main pathological type of polyps was tubular adenoma.Com parison between polyp group and normal group showed that the detection rate of intestinal polyps in the group over 50 years old was higher than that in the group under 50 years old;that in male group was higher than that in fe male group,and that in the group with BMI≥24 was higher than that in the group with BMI<24.Conclusion Among the health examination population,male,BMI≥24,people over 50 years old,and left hemicolon should be the focus of colonoscopy screening.

关 键 词：结直肠息肉 健康体检 肠镜 

分 类 号：R73[医药卫生—肿瘤]