老年慢性脑缺血患者血管性认知功能损害的血管性因素分析  

Analysis of vascular factors of vascular cognitive impairment in elderly patients with chronic cerebral ischemia

作　　者：熊洁[1] 赵俐红[1] 李雳 XIONG Jie;ZHAO Li hong;LI Li(Department of Radiology,West China Hospital,Si chuan University,Chengdu 610041,China)

机构地区：[1]四川大学华西医院放射科

出　　处：《实用医院临床杂志》2019年第6期31-34,共4页Practical Journal of Clinical Medicine

摘　　要：目的探讨老年慢性脑缺血患者血管性认知功能损害(VCI)的血管性因素。方法我院收治的老年慢性脑缺血患者206例。根据蒙特利尔认知评价量表(MoCA)评分结果分为VCI组(MoCA评分≤26分,n=86)和非VCI组(MoCA评分>26分,n=120)。收集患者各项临床资料,分析老年慢性脑缺血患者发生VCI的独立危险因素。结果两组在冠心病、高血压、糖尿病、血脂水平、心房颤动、血清Hcy、hs-CRP水平等方面比较,差异有统计学意义(P<0.05);冠心病、高血压、糖尿病、Hcy偏高、hs-CRP偏高是导致老年慢性脑缺血患者发生VCI的独立危险因素(P<0.05)。结论老年慢性脑缺血患者发生VCI的风险较高,其中冠心病、高血压、糖尿病、血清Hcy、hs-CRP水平偏高的患者更易出现VCI,临床上应对高危患者采取相应措施以期降低VCI发生率。Objective To explore the vascular factors of vascular cognitive impairment(VCI) in elderly patients with chronic cerebral ischemia.Methods A total of 206 elderly patients with chronic cerebral ischemia admitted to our hospital were selected.According to the Montreal Cognitive Rating Scale(MoCA) score,206 patients were divided into VCI group(MoCA score≤26 points,n=86) and non-VCI group(MoCA score> 26 points,n=120).The clinical data of the patients were collected for univariate analysis,and the VCI-related factors were analyzed by unconditional Logistic multiple regression analysis.Results There were statistically significant differences in coronary heart disease,hypertension,diabetes,blood lipids levels,atrial fibrillation and levels of serum Hcy and hs-CRP between the two groups(P <0.05).Unconditional logistic multiple regression analysis showed that coronary heart disease,hypertension,diabetes,high Hcy and high hs-CRP were independent risk factors for VCI in elderly patients with chronic cerebral ischemia(P <0.05).Conclusion The risk of VCI is high in elderly patients with chronic cerebral ischemia.Patients with coronary heart disease,hypertension,diabetes and high levels of serum Hcy and hs-CRP are more likely to have VCI.Clinically,it is necessary to take corresponding measures to high-risk patients so as to reduce the incidence rate of VCI.

关 键 词：慢性脑缺血 老年 血管性认知功能损害 血管性因素 高血压 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R749.2[医药卫生—临床医学]