靶向刀治疗Ⅰ期肺癌临床应用  

Clinical application of targeted knife in treating stage Ⅰ lung cancers

作　　者：徐家华[1] 顾小强[1] 李鑫[1] 熊一白 李宏伟[1] 杨金祖[1] 于观贞 钱建新 武清[1] XU Jiahua;GU Xiaoqiang;LI Xing;XIONG Yibai;LI Hongwei;YANG Jingzu;YU Guanzheng;QIAN Jianxin;WU Qing(Department of Oncology,Affiliated Longhua Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China)

机构地区：[1]上海中医药大学附属龙华医院肿瘤科

出　　处：《介入放射学杂志》2019年第10期958-961,共4页Journal of Interventional Radiology

基　　金：上海市专科疾病临床“五新”转化项目（16CR3039A）

摘　　要：目的探讨国产靶向刀治疗Ⅰ期肺癌方法的近期疗效和安全性。方法收集2016年1月1日至2018年6月30日CT引导下行国产靶向刀冷冻消融治疗术的Ⅰ期肺癌患者24例。通过CT术中冷冻冰球的参数,评价目标病灶完全消融率和近期的局部复发率、手术相关并发症及1年生存率。结果24例完全消融率为100%,在12个月的随访期间,24例患者全部存活,3患者出现术后少量气胸,无咯血,无严重并发症和死亡。结论国产靶向刀治疗Ⅰ期肺癌安全有效,能有效灭活瘤体。Objective To explore the short-term efficacy and safety of domestic cryoablation targeted knife in the treatment of stageⅠlung cancers.Methods A total of 24 patients with stageⅠlung cancer,who underwent CT-guided cryoablation with domestic targeted knife during the period from January 1,2016 to June 30,2018,were collected.The parameters of frozen ice spheres obtained from intraoperative CT scan were used to assess the complete ablation rate,the short-term local recurrence rate,the surgery-related complications and the one-year survival rate.Results The complete ablation rate was 100%.During the follow-up period lasting for 12 months,all 24 patients survived,3 patients had a small amount of pneumothorax after cryoablation.No hemoptysis,serious complications or death occurred.Conclusion For the treatment of stageⅠlung cancers,cryoablation with domestic targeted knife is safe and effective,and the tumor body can be effectively inactivated.

关 键 词：肺癌 冷冻消融 靶向刀 

分 类 号：R734.2[医药卫生—肿瘤]