临床生物样本库应用机制探索  

Analysis of the application mechanism of clinical biobank

作　　者：李海燕 倪明宇 林金嬉[2] 张允[3] 张永宏[4] 蔡彦宁[5] 尤红[3] 王晓民[6] Li Haiyan;Ni Mingyu;Li Jinxi;Zhang Yun;Zhang Yonghong;Cai Yanning;You Hong;Wang Xiaomin(Department of Science and Technology,Capital Medical University,Beijing 100069,China;Beijing Tiantan Hospital,Capital Medical University,Beijing 100050,China;Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China;Beijing Youan Hospital,Capital Medical University,Beijing 100069,China;Xuanwu Hospital,Capital Medical University,Beijing 100053,China;School of Basic Medical Sciences,Capital Medical University,Beijing 100069,China)

机构地区：[1]首都医科大学科技处,北京100069 [2]首都医科大学附属北京天坛医院,100070 [3]首都医科大学附属北京友谊医院,100050 [4]首都医科大学附属北京佑安医院,100069 [5]首都医科大学宣武医院,北京100053 [6]首都医科大学基础医学院,北京100053

出　　处：《中华医学科研管理杂志》2019年第5期397-400,共4页Chinese Journal of Medical Science Research Management

基　　金：国家重点研发计划(2016YFC1201703)。

摘　　要：目的对临床生物样本库的应用现状及存在问题进行分析,提出临床生物样本库的应用机制建议。方法通过问卷调研和案例分析,并结合国内外的相关文献报道,对临床生物样本库的应用现状与问题进行定性分析。结果随着生物样本库的迅速发展,其应用率远没有达到预期,我国在临床数据库建设方面相对滞后,影响样本的应用;应用机制滞后,影响样本库的对外开放和应用。结论临床生物样本库在建设之初,应该充分考虑到如何应用,怎么应用,并建立符合自身特点的应用机制,提供样本库的建设效益。Objective Analyze the application status and existed problems of clinical biobank in China,propose possible application mechanisms for clinical biobank.Methods Through questionnaire survey and case analysis combined with relevant literature reports from home and abroad,conduct qualitative analysis to understand the application status and problems of clinical biobank.Results With the rapid development of biobank,its application rate was far from expected.The construction of clinical database lags behind in China will affect the application of samples.The lag of application mechanism will affect the opening and application of the biobank.Conclusions At the beginning of construction,the clinical biobank should take full account of what and how resources can be used,and establish tailored application mechanism.More attention should be paid to the possible benefit of biobank construction.

关 键 词：生物样本库 应用 共享 精准医学 

分 类 号：G63[文化科学—教育学]