新型快速病理诊断技术在内镜逆行胆胰管造影术下胆管活检中应用的临床价值  

The clinical value of new rapid pathological diagnosis technology inbiliary biopsy by endoscopic retrograde cholangiopancreatography

作　　者：王磊[1] 周明 杨家佳[1] 蒋淑婉[1] 万晓洁 唐嘉阅 马洁 王远志 Wang Lei;Zhou Ming;Yang Jiajia;Jiang Shuwan;Wan Xiaojie;Tang Jiayue;Ma Jie;Wang Yuanzhi(Departmentof Pathology,the Affiliated Hospital of Yangzhou University,Yangzhou 225009,China;Department of General Surgery,the Affiliated Hospital of Yangzhou University,Yangzhou 225009,China;Department of Gastroenterology,the Affiliated Hospital of Yangzhou University,Yangzhou 225009,China)

机构地区：[1]扬州大学附属医院病理科,225009 [2]扬州大学附属医院普外科,225009 [3]扬州大学附属医院消化内科,225009

出　　处：《中国医师杂志》2019年第10期1464-1467,共4页Journal of Chinese Physician

基　　金：江苏省科技厅临床医学科技专项(BL2014064)~~

摘　　要：目的探讨新型快速病理诊断技术在内镜逆行胆胰管造影术(ERCP)下胆管活检中应用的临床价值。方法选择7例ERCP下胆管活检患者,在胆管活检操作过程中采用新型快速病理诊断技术对活检组织滚片进行细胞学初诊,依据快速病理诊断结果调整活检操作预案,分析新型快速病理诊断技术在ERCP下胆管活检中的临床价值。结果新型快速病理诊断技术开展所需空间小,无污染,诊断耗时约2~3 min,不影响正常活检操作。7例ERCP下胆管活检患者中,5例(71.4%)在本技术协助下确认首次活检达到活检质与量的要求,2例(28.6%)再次活检后达到活检质与量的要求。结论由于ERCP下胆管活检时具有一定的盲目性,因而活检组织的质与量往往不能得到保证。新型快速病理诊断技术可在ERCP下胆管活检过程中提供实时病理诊断,提高胆管活检组织的质与量,且本技术开展成本低,适宜在各级医院推广施行。Objective To explore the clinical value of new rapid pathological diagnosis technology in biliary biopsy by endoscopic retrograde cholangiopancreatography(ERCP).Methods 7 patients with biliary biopsy by ERCP were selected.In the biliary biopsyoperation,a new type of rapid pathological diagnostic technique is used to perform cytological initial diagnosis of the biopsy tissue.According to the results of rapid pathological diagnosis of biliary biopsy operation,we analyzed the clinical value of new rapid pathological diagnosis technology in the biliary biopsy operation.Results The new rapid pathological diagnosis technology requires little space and no pollution.The diagnosis takes about 2 to 3 minutes and does not affect the normal biopsy operation.7 patients with biliary biopsy by ERCP under the assistance of this technique,5 patients(71.4%)confirmed the requirement of biopsy quality and quantity for the first biopsy with the assistance of this technology and 2 patients(28.6%)met the requirements for biopsy quality and quantity after biopsy again.Conclusions Because of the blindness of biliary biopsy by ERCP,the quality and quantity of biopsy tissue are often not guaranteed.The new rapid pathological diagnosis technology can provide real-time pathological diagnosis during biliary biopsy by ERCP and improve the quality and quantity of biliary biopsy tissue,and the cost of this technology is low,which is suitable for popularization and implementation in hospitals at all levels.

关 键 词：胰胆管造影术 内窥镜逆行 影像引导活检 胆管肿瘤 病理学 临床 

分 类 号：R73[医药卫生—肿瘤]