普通内镜与pit pattern分型在结直肠肿瘤中的病理诊断及浸润深度判断  

Pathological diagnosis and evaluation of infiltration depth of colorectal tumour by ordinary endoscopy and pit pattern typing

作　　者：朱振华 冯一中[2] ZHU Zhen-hua;FENG Yi-zhong(Fenhu Hospital,the First People's Hospital of Wujiang District/the Fifth People's Hospital of Wujiang District,Suzhou 215211;the Second Affiliated Hospital of Suzhou University,Suzhou 215004,China)

机构地区：[1]江苏省吴江区第一人民医院汾湖院区/吴江区第五人民医院,江苏苏州215211 [2]苏州大学附属第二医院,江苏苏州215004

出　　处：《临床医学研究与实践》2019年第32期10-11,30,共3页Clinical Research and Practice

摘　　要：目的探讨普通内镜与pit pattern分型在结直肠肿瘤中的病理诊断及浸润深度。方法回顾性分析2014年4月至2017年4月因锯齿状腺瘤(SA)于我院消化科进行治疗的30例患者的SA内镜及病理学资料,比较病理诊断及肿瘤浸润深度判断结果。结果本研究中,内镜检出了35枚SA,隆起型和表面型分别21、14枚,两种类型的SA平均直径分别为10.5、16.5 mm。10 mm以下的SA上皮内瘤变多于10 mm以上的SA上皮瘤变。pit pattern分型中,共有Ⅱ型23枚,Ⅲ型11枚,Ⅳ型1枚。按照腺体上皮内瘤变的级别,其中Ⅰ、Ⅱ、Ⅲ级分别为28、6、1枚。SA的pit pattern分型与病理学分型、上皮内瘤变级别有显著相关性(χ^2=20.035、18.320,P=0.000)。结论 SA具有息肉肿瘤学的一般生物学行为,与结直肠癌的发病密切相关,在临床检查中应该给予高度的重视。Objective To investigate the pathological diagnosis and infiltration depth of colorectal tumour by ordinary endoscopy and pit pattern typing. Methods The endoscopic and pathological data of 30 patients with serrated adenoma(SA)treated in digestive department of our hospital from April 2014 to April 2017 were retrospectively analyzed, and the results of pathological diagnosis and infiltration depth of tumor were compared. Results In this study, 35 SA were detected by endoscopy, there were 21 protruded type and 14 surface type, respectively. The average diameter of SA of the two types were 10.5 and 16.5 mm, respectively. SA intraepithelial neoplasia less than 10 mm was more than SA intraepithelial neoplasia more than 10 mm. Among the pit patterns, there were 23 type Ⅱ, 11 type Ⅲ and 1 type Ⅳ. According to the grade of intraepithelial neoplasia, there were 28, 6 and 1 in grade Ⅰ, Ⅱ and Ⅲ, respectively. The molecular type of SA was significantly correlated with histological type and grade of intraepithelial neoplasia(χ^2=20.035, 18.320, P =0.000).Conclusion SA has the general biological behavior of polyp oncology, it is closely related to the incidence of colorectal tumour, which should be paid more attention in clinical examination.

关 键 词：普通内镜 PIT PATTERN 分型 结直肠肿瘤 病理诊断 浸润深度 

分 类 号：R735.2[医药卫生—肿瘤]