不同激素受体乳腺癌的临床病理特征、治疗及生存分析  

Clinicopathological Characteristics,Treatment and Survival Analysis of Different Hormone Receptor Breast Cancer

作　　者：王海燕[1] WANG Haiyan(Department of Pathology,Wujin Hospital of Traditional Chinese Medicine,Changzhou Jiangsu 213161,China)

机构地区：[1]江苏省常州市武进中医医院病理科,江苏常州213161

出　　处：《大医生》2019年第9期50-52,共3页Doctor

摘　　要：目的分析不同激素受体(HR)乳腺癌的临床病理特点、治疗措施以及预后效果。方法收集2016年1月至2019年3月江苏省常州市武进中医医院诊治的103例乳腺癌患者,分析患者的临床特点、治疗措施与生存期。结果所有患者年龄25~78岁,平均年龄(52.3±4.3)岁,其中HR(-)27例,与HR(-)患者比较,HR(+)患者的无病生存期与总生存期均较长,差异有统计学意义(P<0.05);临床治疗中,内分泌治疗有利于改善HR(+)患者无病生存期与总生存期;中药辅助治疗有利于延长所有患者的无病生存期与总生存期,组间比较差异有统计学意义(P<0.05);且HR(-)患者服用中药可提高3年无病生存期。结论激素受体状态为乳腺癌患者的独立预后因素,内分泌治疗有利于改善激素受体阳性乳腺癌患者预后,联合中药治疗可延缓病情复发,对于激素受体阴性患者中药治疗同样可获益。Objective To analyze the clinicopathological features,treatment measures and prognosis of different hormone receptor(HR)breast cancer.Methods A total of 103 breast cancer patients from January 2016 to March 2019 in Wujin Chinese Medicine Hospital of Changzhou City,Jiangsu Province were enrolled.The clinical characteristics,treatment measures and survival time of the patients were analyzed.Results All patients were 25-78 years old,with an average age of(52.3±4.3)years,including 27 cases of HR(-).Compared with HR(-)patients,HR(+)patients had disease-free survival and overall survival.Long,the difference was statistically significant(P<0.05);in clinical treatment,endocrine therapy is beneficial to improve the disease-free survival and overall survival of HR(+)patients;Chinese medicine adjuvant therapy is beneficial to prolong the disease-free survival of all patients.The overall survival,the difference between the groups was statistically significant(P<0.05);and HR(-)patients taking Chinese medicine can improve the disease-free survival of 3 years.Conclusion The hormone receptor status is an independent prognostic factor for breast cancer patients.Endocrine therapy is beneficial to improve the prognosis of patients with hormone receptor-positive breast cancer.Combined with traditional Chinese medicine treatment can delay the recurrence of the disease,and it can also benefit Chinese medicine treatment for hormone receptor-negative patients.

关 键 词：乳腺癌 激素受体 病理特征 

分 类 号：R73[医药卫生—肿瘤]