结肠癌患者术后开始化疗时机对患者远期预后的影响  

The Effect of Timing of Chemotherapy on Long-term Prognosis of Patients with Colon Cancer after Operation

作　　者：王迪 WANG Di(Tonghua Central Hospital,Tonghua,Jilin 134000)

机构地区：[1]吉林省通化市中心医院

出　　处：《智慧健康》2019年第29期195-196,共2页Smart Healthcare

摘　　要：目的研讨结肠癌手术后不同化疗时机对结肠癌患者远期预后的影响。方法根据化疗时机的不同对40例结肠癌手术患者进行分组,A组(n=20)于术后2周实施化疗,B组(n=20)于术后3周实施化疗,对两组的远期预后进行观察与评估。结果A组与B组在化疗期间出现的不良反应率对比,P>0.05,无统计学意义。A组化疗后1年的复发率、远处转移率相比B组均显著降低,P<0.05,有统计学意义;但1年存活率、2年存活率对比,P>0.05,无统计学意义。结论在结肠癌术后2周实施化疗治疗,整体效果较术后3周化疗理想,值得推荐。Objective To study the effect of different chemotherapy time on long-term prognosis of patients with colon cancer after operation.Methods Forty colon cancer patients were divided into two groups according to the timing of chemotherapy.Group A(n=20)received chemotherapy 2 weeks after operation and group B(n=20)received chemotherapy 3 weeks after operation.The long-term prognosis of the two groups was observed and evaluated.Results The adverse reactions of group A and group B during chemotherapy were compared,P>0.05,with no statistical significance.The recurrence rate and distant metastasis rate of group A after 1 year of chemotherapy were significantly lower than those of group B,P<0.05,with statistical significance,but there was no significant difference between 1-year survival rate and 2-year survival rate(P>0.05).Conclusion Chemotherapy was performed 2 weeks after operation for colon cancer.The overall effect was better than that of chemotherapy 3 weeks after operation.It is worth recommending.

关 键 词：结肠癌手术 化疗时机 结肠癌 远期预后 

分 类 号：R73[医药卫生—肿瘤]