冲动性不同维度对酒依赖患者复饮的影响  

The effects of different dimensions of impulsivity on relapse in patients with alcohol dependence

作　　者：樊运莉 王军凯[3] 李芹 牛雅娟[4] 杨楹[2] 孙洪强[1] FAN Yunli;WANG Junkai;LI Qin(Peking University Sixth Hospital,Beijing 100191,China)

机构地区：[1]北京大学第六医院,北京市100191 [2]山东省精神卫生中心 [3]北京大学 [4]北京回龙观医院

出　　处：《精神医学杂志》2019年第2期92-95,共4页Journal of Psychiatry

摘　　要：目的比较酒依赖患者和健康对照、复饮者与未复饮者之间的冲动性差异,并从冲动性的不同维度探讨冲动性不同维度对酒依赖复饮的影响。方法选取酒依赖患者(研究组)41例和健康对照(对照组)22例,分别进行Barratt-11冲动性量表(BIS-11)、延迟折扣任务(DDT)、气球模拟风险任务(BART)和GO/NO-GO任务测试。对酒依赖患者进行出院后3个月的随访,分为复饮组和未复饮组,分析冲动性不同维度对酒依赖复饮的影响。结果研究组BIS-11总分及注意冲动性、BART、DDT评分均高于对照组(P<0.05)。复饮组DDT评分高于未复饮组(P<0.05)。Logistic回归分析结果显示,延迟折扣率的自然对数lnk是酒依赖复饮发生的危险因素(P<0.05)。结论酒依赖患者在注意冲动性方面和认知冲动性(气球模拟风险和延迟折扣)方面冲动性高。酒精复饮者在延迟折扣方面明显高于未复饮者,且延迟折扣与酒依赖的复饮密切相关,是酒依赖复饮发生的危险因素。Objective To compare the impulsivity differences between patients with alcohol dependence and healthy controls,between relapsers and abstainers,and to explore the effects of different impulsivity dimensions on relapse.Methods A total of 41 male alcohol-dependent inpatients(study group)and 22 healthy controls(control group)were selected and assessed with Barratt Impulsiveness Scale(BIS-11),Delay Discounting Task(DDT),Balloon Analogue Risk Task(BART)and GO/NO-GO task.After the 3-month follow-up,alcohol-dependent patients were divided into relapsers and abstainers,to explore the effects of different impulsivity dimensions on relapse.Results The total score and factor score of attention impulsivity of BIS-11,the total scores of BART and DDT in study group were all significantly higher than those in control group(P<0.05).The total score of DDT in relapser group was significantly higher than that in abstainer group(P<0.05).Logistic regression analysis showed that the natural logarithm lnk of delay discounting rate in DDT task was a risk factor of alcohol dependence relapse(P<0.05).Conclusion Compared with healthy controls,alcohol-dependent patients show higher levels of impulsivity,especially in attention impulsivity and cognitive impulsivity(balloon analogue risk and delay discounting).Relapsers show higher DDT score than abstainers;delay discounting rate in DDT task is closely related to relapse and is a risk factor for alcohol dependence relapse.

关 键 词：酒依赖 冲动性 复饮 

分 类 号：R749.62[医药卫生—神经病学与精神病学]