西安市某医院成人与儿童血清25羟基维生素D水平的研究  

Study on Serum 25-hydroxyvitamin D Levels in Adults and Children in a Hospital in Xi’an

作　　者：任晓兵 徐蓓[3] 陈广福[2] 张婕钰[2] 朱克修 REN Xiao-bing;XU Bei;CHEN Guang-fu;ZHANG Jie-yu;ZHU Ke-xiu(Xi'an Jiaotong University Health Science Center,Xi'an,Shaanxi,710061,China;Laboratory of Gynecology,Xi'an Gaoxin Hospital,Xi'an,Shaanxi,710075,China;Department of Laboratory Medicine,Xi'an Children's Hospital,Xi'an,Shaanxi,710003,China;Department of Gynecology and Obstetrics,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an,Shaanxi,710061,China)

机构地区：[1]西安交通大学医学部,陕西西安710061 [2]西安高新医院妇科实验室,陕西西安710075 [3]西安市儿童医院检验科,陕西西安710003 [4]西安交通大学第一附属医院妇产科,陕西西安710061

出　　处：《现代生物医学进展》2019年第20期3853-3856,4000,共5页Progress in Modern Biomedicine

基　　金：国家自然科学基金项目(31370193)

摘　　要：目的:比较西安市某医院不同年龄段的成人与儿童血清25羟基维生素D(25-OH-VD)水平,并探讨其水平与年龄之间的关系。方法:收集2017年1月-2018年1月西安高新医院检测血清25-OH-VD的2116例样本,比较成人与儿童血清中25-OH-VD水平的差异,分析成人与儿童血清中25-OH-VD水平与年龄之间的关系。结果:儿童组健康人群、低水平人群血清25-OH-VD水平均高于成人组(P<0.05);儿童组健康人群、低水平人群血清25-OH-VD水平与年龄呈负相关(P<0.05),成人组健康人群血清25-OH-VD水平与年龄呈正相关(P<0.05)。结论:西安市某医院的儿童血清25-OH-VD水平高于成人,且成人与儿童的血清25-OH-VD水平与年龄存在一定的关系,有必要建立不同的参考区间,为临床诊治提供更精确的依据。Objective: To compare the serum 25-hydroxyvitamin D(25-OH-VD) levels in adults and children with different ages in a hospital in Xi’an, and to explore the relationship between the levels and age. Methods: A total of 216 serum samples of 25-OH-VD in Xi’an Gao-xin Hospital from January 2017 to January 2018 were collected. The serum 25-OH-VD levels were compared between adults and children, the relationship between serum 25-OH-VD levels and age in adults and children was analyzed. Results: Serum 25-OH-VD levels in healthy people and low-level people in the children group were higher than those in the adult group(P<0.05). Serum 25-OH-VD levels in healthy and low-level children were negatively correlated with age(P<0.05). Serum 25-OH-VD levels in healthy people in the adults group was positively correlated with age(P<0.05). Conclusion: The serum 25-OH-VD levels of children in a hospital in Xi’an are higher than that of adults, and there is a certain relationship between the serum 25-OH-VD levels of adults and children and age.It is necessary to establish different reference intervals to provide more accurate basis for clinical diagnosis and treatment.

关 键 词：西安 25羟基维生素D 儿童 成人 年龄 

分 类 号：R153.2[医药卫生—营养与食品卫生学] Q565[医药卫生—公共卫生与预防医学]