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作 者:周楠 魏文斌 Zhou Nan;Wei Wenbin(Beijing Tongren Eye Center,Beijing key Laboratory of Intraocular Tumor Diagnosis and Treatment,Beijing Ophthalmology&Visual Sciences Key Lab,Beijing Tongren Hospital,Capital Medical University,Medical Artificial Intelligence Research and Verification Laboratory of Ministry of Industry and Information Technology,Beijing 100730,China)
机构地区:[1]首都医科大学附属北京同仁医院,北京同仁眼科中心,北京市眼科学与视觉科学重点实验室,眼内肿瘤诊治研究北京市重点实验室,工信部医学人工智能研究与验证实验室,100730
出 处:《中华眼底病杂志》2019年第6期615-617,共3页Chinese Journal of Ocular Fundus Diseases
基 金:国家自然科学基金(81570891、81272981);眼内肿瘤诊治研究北京市重点实验室2015年度科技创新基地培育与发展专项项目(Z151100001615052)。
摘 要:目前对于板层黄斑裂孔相关视网膜前增生膜(LHEP)的认识主要依赖于OCT检查所见,在黄斑板层裂孔(LMH)的边缘可见这种视网膜前增生表现为线状强反射下的中强反射物质,位于内界膜和神经纤维层之间。但LHEP的组织来源、形态学及OCT影像特征等均与LMH有区别,视力预后也更差。目前对LHEP的发生与临床预后的关系等尚在研究之中。本文阐述LHEP病理学、形态学、临床特征及诊疗、预后研究现状及进展,以期增强临床对该病的认识。The current understanding of lamellar hole-associated epiretinal proliferation(LHEP)is based on OCT examination.This preretinal proliferation is seen at the edge of the lamina macular hole(LMH)as a meso-reflective substance under linear strong reflection,located between the internal limiting membranes and the nerve fiber layer.LHEP is often associated with LMH,but its histological origin,morphology and OCT characteristics are different from LMH,and its visual prognosis is worse.At present,the relationship between the occurrence of LHEP and clinical prognosis is still under study.This article reviews the pathology,morphology,clinical features,diagnosis and treatment of LHEP,in order to enhance clinical understanding of this disease.
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